日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Chromosome centromere copy number amplification associated with exceptional response in HER2-positive metastatic breast cancer patients

染色体着丝粒拷贝数扩增与HER2阳性转移性乳腺癌患者的卓越疗效相关

期刊:Oncogene
影响因子:7.3
doi:10.1038/s41388-025-03667-8
Andrieu, Charlotte; Stoof, Jojanneke; AlSultan, Dalal; Ivers, Laura; Berenguer Pina, Jose Javier; Skrobo, Darko; Ballot, Jo; O'Reilly, Debbie; Collins, Denis M; Eustace, Alex J; Quinn, Cecily; Walshe, Janice M; Gullo, Giuseppe; Walsh, Naomi; Crown, John
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2026
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Translating Basic Science Discoveries into Clinical Advances: Highlights from the EACR-AACR-IACR 2024 Conference in Celebration of Irish Association for Cancer Research's 60th Anniversary

将基础科学发现转化为临床进展：2024年EACR-AACR-IACR会议亮点回顾，庆祝爱尔兰癌症研究协会成立60周年

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17091420
Lynch, Seodhna M; Richards, Cathy E; Ui Mhaonaigh, Aisling; Lynam-Lennon, Niamh; Eustace, Alex J; Allott, Emma H; Robson, Tracy; Marcone, Simone
肿瘤
肿瘤免疫
发表日期：2025
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TP53 Mutation-Specific Dysregulation of Store-Operated Calcium Entry and Apoptotic Sensitivity in Triple-Negative Breast Cancer.

TP53 突变特异性导致三阴性乳腺癌中储存操纵性钙离子内流和细胞凋亡敏感性失调

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17101614
Rabab Kaneez E, Buchanan Paul J, Colley Grace, White Anita, Murphy Aisling, McCormack Chloe, Eustace Alex J
细胞生物学
乳腺癌
P53
凋亡
发表日期：2025
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TCHL - a phase II neo-adjuvant study assessing TCH (docetaxel, carboplatin and trastuzumab) and TCHL (docetaxel, carboplatin, trastuzumab and lapatinib) in HER-2 positive breast cancer patients: a 5-year follow-up with serum biomarker analysis

TCHL——一项评估TCH（多西他赛、卡铂和曲妥珠单抗）和TCHL（多西他赛、卡铂、曲妥珠单抗和拉帕替尼）方案在HER-2阳性乳腺癌患者中疗效的II期新辅助治疗研究：一项为期5年的随访研究及血清生物标志物分析

期刊:Acta Oncologica
影响因子:2.2
doi:10.2340/1651-226X.2025.43143
Crown, John; Eustace, Alex J; Collins, Denis M; Keane, Maccon; Coate, Linda; Kennedy, John; O'Reilly, Seamus; Kelly, Catherine; O'Connor, Miriam; Martin, Michael; Murphy, Conleth; Duffy, Karen; Walshe, Janice; Gullo, Giuseppe; Mahgoub, Thamir; Alvarez-Iglesias, Alberto; Parker, Imelda; Donachie, Vicky; Teiserskiene, Ausra; Madden, Stephen F; Moulton, Brian; O'Donovan, Norma; Hennessy, Bryan T
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Precision Oncology, Artificial Intelligence, and Novel Therapeutic Advancements in the Diagnosis, Prevention, and Treatment of Cancer: Highlights from the 59th Irish Association for Cancer Research (IACR) Annual Conference

精准肿瘤学、人工智能和癌症诊断、预防和治疗领域的新型疗法进展：第59届爱尔兰癌症研究协会（IACR）年会亮点

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers16111989
Lynch, Seodhna M; Heeran, Aisling B; Burke, Caoimbhe; Lynam-Lennon, Niamh; Eustace, Alex J; Dean, Kellie; Robson, Tracy; Rahman, Arman; Marcone, Simone
肿瘤
肿瘤免疫
发表日期：2024
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Predictive modelling of response to neoadjuvant therapy in HER2+ breast cancer

HER2阳性乳腺癌新辅助治疗反应的预测模型

期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-023-00572-9
Cosgrove, Nicola; Eustace, Alex J; O'Donovan, Peter; Madden, Stephen F; Moran, Bruce; Crown, John; Moulton, Brian; Morris, Patrick G; Grogan, Liam; Breathnach, Oscar; Power, Colm; Allen, Michael; Walshe, Janice M; Hill, Arnold D; Blümel, Anna; O'Connor, Darren; Das, Sudipto; Milewska, Małgorzata; Fay, Joanna; Kay, Elaine; Toomey, Sinead; Hennessy, Bryan T; Furney, Simon J
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2023
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Aberrant calcium signalling downstream of mutations in TP53 and the PI3K/AKT pathway genes promotes disease progression and therapy resistance in triple negative breast cancer

TP53和PI3K/AKT通路基因突变导致的下游异常钙信号传导促进三阴性乳腺癌的疾病进展和治疗耐药性。

期刊:Cancer Drug Resistance
影响因子:5.2
doi:10.20517/cdr.2022.41
Eustace, Alex J; Lee, Min Jie; Colley, Grace; Roban, Jack; Downing, Tim; Buchanan, Paul J
肿瘤
肿瘤免疫
信号转导
治疗耐药
乳腺癌
P53
AKT
发表日期：2022
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Precision Medicine and Novel Therapeutic Strategies in Detection and Treatment of Cancer: Highlights from the 58th IACR Annual Conference

精准医疗与癌症检测和治疗中的新型治疗策略：第58届国际癌症研究协会年会亮点

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers14246213
Kennedy, Sean P; Treacy, Oliver; Allott, Emma H; Eustace, Alex J; Lynam-Lennon, Niamh; Buckley, Niamh; Robson, Tracy
肿瘤
肿瘤免疫
发表日期：2022
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RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer

回复：RNA破坏检测作为新辅助曲妥珠单抗治疗的人表皮生长因子受体2阳性乳腺癌病理完全缓解的生物标志物

期刊:Jnci-Journal of the National Cancer Institute
影响因子:7.2
doi:10.1093/jnci/djw111
Toomey, Sinead; Eustace, Alex J; Pritzker, Laura B; Pritzker, Ken P H; Fay, Joanna; O'Grady, Anthony; Cummins, Robert; Grogan, Liam; Kennedy, John; O'Connor, Darran; Young, Leonie; Kay, Elaine W; O'Donovan, Norma; Gallagher, William M; Kalachand, Roshni; Crown, John; Hennessy, Bryan T
肿瘤
肿瘤免疫
信号转导
乳腺癌
Human
发表日期：2016
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The impact of ERBB-family germline single nucleotide polymorphisms on survival response to adjuvant trastuzumab treatment in HER2-positive breast cancer

ERBB家族种系单核苷酸多态性对HER2阳性乳腺癌患者接受曲妥珠单抗辅助治疗后生存反应的影响

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.12782
Toomey, Sinead; Madden, Stephen F; Furney, Simon J; Fan, Yue; McCormack, Mark; Stapleton, Carragh; Cremona, Mattia; Cavalleri, Gianpiero L; Milewska, Malgorzata; Elster, Naomi; Carr, Aoife; Fay, Joanna; Kay, Elaine W; Kennedy, Susan; Crown, John; Gallagher, William M; Hennessy, Bryan T; Eustace, Alex J
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2016
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