日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

组蛋白去乙酰化酶抑制剂丙戊酸与 DNA 损伤药物玫瑰树碱在神经母细胞瘤细胞中发挥协同细胞毒性

Tereza Cerna, Jan Hrabeta, Tomas Eckschlager, Eva Frei, Heinz H Schmeiser, Volker M Arlt, Marie Stiborová

Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1

活性位点突变是解释马兜铃酸 I 硝基还原机制的合适工具,该机制由细胞色素 P450 1A1、1A2 和 1B1 进行

Jan Milichovský, František Bárta, Heinz H Schmeiser, Volker M Arlt, Eva Frei, Marie Stiborová, Václav Martínek

Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2

人类细胞色素 P450 1A1 和 1A2 对尿路上皮致癌物马兜铃酸 I 的生物活化与解毒

Marie Stiborová, Katerina Levová, Frantisek Bárta, Zhanquan Shi, Eva Frei, Heinz H Schmeiser, Daniel W Nebert, David H Phillips, Volker M Arlt