Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity.
亨廷顿蛋白形成有毒的 NH2 末端片段复合物，而蛋白酶体活性随年龄增长而降低，促进了这种复合物的形成
期刊:Journal of Cell Biology
影响因子:6.4
doi:10.1083/jcb.200306038
Zhou Hui, Cao Fengli, Wang Zhishan, Yu Zhao-Xue, Nguyen Huu-Phuc, Evans Joy, Li Shi-Hua, Li Xiao-Jiang
