日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs)

通过对一系列新型检测方法(NAMs)中全氟和多氟烷基物质(PFAS)库进行测试,获得了以下见解

Patlewicz, Grace; Judson, Richard; Paul Friedman, Katie; Wetmore, Barbara A; DeVito, Michael J; Harrill, Joshua A; Carstens, Kelly E; Houck, Keith A; Wambaugh, John F; Padilla, Stephanie; Britton, Katy N; Shafer, Timothy J; Degitz, Sigmund; Nyffeler, Jo; Kreutz, Anna; Richard, Ann M; Williams, Antony J; Coutros, Katherine; Hornung, Michael W; Cowden, John; Everett, Logan J; Willis, Clinton M; Smeltz, Marci G; Clifton, M Scott; Feshuk, Madison; Wall, Jonathan T; Sayre, Risa R; Brown, Jason; Thomas, Russell S

Integrating Transcriptomic and Targeted New Approach Methodologies into a Tiered Framework for Chemical Bioactivity Screening

将转录组学和靶向新方法整合到分层框架中,用于化学生物活性筛选

Rogers, Jesse D; Bundy, Joseph L; Harrill, Joshua A; Judson, Richard J; Paul-Friedman, Katie; Everett, Logan J

Transcriptomic dose response assessment of PFAS chemicals 3:3 fluorotelomer carboxylic acid, 7:3 fluorotelomer alcohol, and perfluorohexanesulfonamide

PFAS 化学物质 3:3 氟调聚物羧酸、7:3 氟调聚物醇和全氟己烷磺酰胺的转录组剂量反应评估

Mutlu, Esra; Wehmas, Leah; Harrill, Alison H; Devito, Michael; Thomas, Russell S; Hughes, Michael F; Macmillan, Denise; Brennan, Amanda; Bounds, Jackson; Weitekamp, Chelsea A; Everett, Logan J

TempO-seq and RNA-seq gene expression levels are highly correlated for most genes: A comparison using 39 human cell lines

TempO-seq 和 RNA-seq 基因表达水平对大多数基因而言高度相关:一项使用 39 种人类细胞系的比较研究

Word, Laura J; Willis, Clinton M; Judson, Richard S; Everett, Logan J; Davidson-Fritz, Sarah E; Haggard, Derik E; Chambers, Bryant A; Rogers, Jesse D; Bundy, Joseph L; Shah, Imran; Sipes, Nisha S; Harrill, Joshua A

High-Throughput Transcriptomics of Water Extracts Detects Reductions in Biological Activity with Water Treatment Processes

水提取物高通量转录组学检测水处理过程中生物活性的降低

Rogers, Jesse D; Leusch, Frederic D L; Chambers, Bryant; Daniels, Kevin D; Everett, Logan J; Judson, Richard; Maruya, Keith; Mehinto, Alvine C; Neale, Peta A; Paul-Friedman, Katie; Thomas, Russell; Snyder, Shane A; Harrill, Joshua

A new approach methodology to identify tumorigenic chemicals using short-term exposures and transcript profiling

利用短期暴露和转录组分析识别致瘤化学物质的新方法

Ledbetter, Victoria; Auerbach, Scott; Everett, Logan J; Vallanat, Beena; Lowit, Anna; Akerman, Gregory; Gwinn, William; Wehmas, Leah C; Hughes, Michael F; Devito, Michael; Corton, J Christopher

Signature analysis of high-throughput transcriptomics screening data for mechanistic inference and chemical grouping

利用高通量转录组学筛选数据进行特征分析,以进行机制推断和化学分组

Harrill, Joshua A; Everett, Logan J; Haggard, Derik E; Word, Laura J; Bundy, Joseph L; Chambers, Bryant; Harris, Felix; Willis, Clinton; Thomas, Russell S; Shah, Imran; Judson, Richard

High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells

利用高通量转录组学筛选ToxCast化学物质对U-2 OS细胞的影响

Bundy, Joseph L; Everett, Logan J; Rogers, Jesse D; Nyffeler, Jo; Byrd, Gabrielle; Culbreth, Megan; Haggard, Derik E; Word, Laura J; Chambers, Bryant A; Davidson-Fritz, Sarah; Harris, Felix; Willis, Clinton; Paul-Friedman, Katie; Shah, Imran; Judson, Richard; Harrill, Joshua A

Editorial: In vitro toxicogenomics (TGx) in hazard and risk assessment

社论:体外毒理基因组学(TGx)在危害和风险评估中的应用

Beal, Marc A; Everett, Logan J

From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow

从愿景到最佳实践:利用统一的工作流程评估体外转录组学在风险评估中的应用。

Reardon, Anthony J F; Farmahin, Reza; Williams, Andrew; Meier, Matthew J; Addicks, Gregory C; Yauk, Carole L; Matteo, Geronimo; Atlas, Ella; Harrill, Joshua; Everett, Logan J; Shah, Imran; Judson, Richard; Ramaiahgari, Sreenivasa; Ferguson, Stephen S; Barton-Maclaren, Tara S