日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

利用毒理病理学最佳实践优化医疗器械的非临床生物学评价

Funk, Kathleen A; Schuh, JoAnn C L; Bolon, Brad; Thomas, Valerie S; Everitt, Jeffrey I; Nyska, Abraham; Paulin, Jaime

SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.

SARS-CoV-2 感染可诱导促纤维化和促血栓形成的泡沫细胞形成。

Battaglia Diana M, Post Claire E, Yao Wenbo, Wahl Angela, Gralinski Lisa E, Liu Hongwei, Dang Hong, Madden Victoria J, White Kristen K, Leist Sarah R, Dinnion Kenneth H 3rd, De la Cruz Gabriela, Midkiff Bentley R, Froggatt Heather M, Gully Kendra, Zweigart Mark, Reader J Rachel, Olstad Katherine J, Everitt Jeffrey I, Van Rompay Koen K A, De Paris Kristina, Sajti Eniko, Pickles Raymond J, Browne Edward P, Jones Corbin D, Boucher Richard C Jr, Baric Ralph S, Garcia J Victor

SCORT-Cas13d Nanotherapy Precisely Targets the 'Undruggable' Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo.

SCORT-Cas13d纳米疗法在体内精准靶向转移性前列腺癌中的“不可成药”转录因子HoxB13

Cui Zhifen, Huang Furong, Fang Kun, Yan Jingyue, Zhang Yuebao, Kang Diana D, Zhou Yufan, Zhao Yue, Everitt Jeffrey I, Hankey William, Armstrong Andrew J, Huang Jiaoti, Wang Hongyan, Jin Victor X, Dong Yizhou, Wang Qianben

Leptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma.

瘦素可增强 IL-13 诱导的气道嗜酸性粒细胞和粘膜下嗜酸性粒细胞增多症,从而引起肥胖相关性哮喘

Ingram Jennifer L, McQuade Victoria L, Weiss Jasmine, Womble Jack T, Ihrie Mark D, Zhao Karen, Francisco Dave, Theriot Barbara, May Katelynn, Kim Haein, McCravy Matthew, Sauler Maor, Lugogo Njira L, Sunday Mary E, Everitt Jeffrey, Walker Julia K L, Tighe Robert M, Kraft Monica, Que Loretta G

Nrf2 hyperactivation as a driver of radiotherapy resistance and suppressed anti-tumor immunity in head and neck squamous cell carcinoma.

Nrf2 过度激活是头颈部鳞状细胞癌放射治疗耐药性和抗肿瘤免疫抑制的驱动因素

Patel Rutulkumar, Saab Kalil, Luo Lixia, Ma Yan, Osman Rashid Abdullah, Williams Nerissa T, Everitt Jeffrey, Zelazowski Maciej J, Castro Patricia, Decker William K, Hudson William H, Myers Jeffrey N, Sandulache Vlad C, Frederick Mitchell J, Mowery Yvonne M, Kirsch David G

Single-dose cathepsin L CRISPR nanotherapy mitigates PASC-like lung damage in hamsters

单剂量组织蛋白酶L CRISPR纳米疗法可减轻仓鼠PASC样肺损伤

Cui, Zhifen; Liu, Tianxiang; Bacon, Rebecca; Zhao, Yue; Everitt, Jeffrey I; Yan, Jingyue; Chen, Lingye; Huang, Jiaoti; Wang, Hongyan; Dong, Yizhou; Jin, Victor X; Liu, Shan-Lu; Wang, Qianben

Efficacious genome editing in infant mice with glycogen storage disease type Ia

在患有 Ia 型糖原贮积症的幼鼠中进行有效的基因组编辑

Arnson, Benjamin; Ilich, Ekaterina; von Beck, Troy; Li, Songtao; Brooks, Elizabeth D; Gheorghiu, Dorothy; He, Gordon; Weinrub, Matthew; Chan, Sze Ying; Kang, Hye-Ri; Courtney, David; Everitt, Jeffrey I; Cullen, Bryan R; Koeberl, Dwight D

MR histology reveals tissue features beneath heterogeneous MRI signal in genetically engineered mouse models of sarcoma

磁共振组织学揭示了基因工程小鼠肉瘤模型中异质性磁共振信号下的组织特征

Blocker, Stephanie J; Mowery, Yvonne M; Everitt, Jeffrey I; Cook, James; Cofer, Gary Price; Qi, Yi; Bassil, Alex M; Xu, Eric S; Kirsch, David G; Badea, Cristian T; Johnson, G Allan

Targeting glutamine dependence with DRP-104 inhibits proliferation and tumor growth of castration-resistant prostate cancer

利用 DRP-104 靶向谷氨酰胺依赖性可抑制去势抵抗性前列腺癌的增殖和肿瘤生长。

Moon, David; Hauck, J Spencer; Jiang, Xue; Quang, Holly; Xu, Lingfan; Zhang, Fan; Gao, Xia; Wild, Robert; Everitt, Jeffrey I; Macias, Everardo; He, Yiping; Huang, Jiaoti

Spontaneous episodic inflammation in the intestines of mice lacking HNF4A is driven by microbiota and associated with early life microbiota alterations

缺乏 HNF4A 的小鼠肠道中自发性间歇性炎症是由肠道菌群驱动的,并且与早期生命阶段的肠道菌群改变有关。

Kelly, Cecelia; Jawahar, Jayanth; Davey, Lauren; Everitt, Jeffrey I; Galanko, Joseph A; Anderson, Chelsea; Avendano, Jonathan E; McCann, Jessica R; Sartor, R Balfour; Valdivia, Raphael H; Rawls, John F