日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Off-label drug use in oncology: integrating molecular and genetic analysis in an academic center's real-world approach

肿瘤学中的超适应症用药:将分子和遗传分析整合到学术中心的实际应用中

Cioli, E; Suarato, G; Napolitano, R; Caraglia, F; Esposito, A; Giugliano, C M; Cozzolino, S; Forte, M; Laudato, M P; Martinelli, E; De Vita, F; Morgillo, F; Orditura, M; Fasano, M; Napolitano, S; Della Corte, C M; Martini, G; Ciardiello, F; Troiani, T; De Falco, V

Triple blockade of EGFR, MEK and PD-L1 has antitumor activity in colorectal cancer models with constitutive activation of MAPK signaling and PD-L1 overexpression

EGFR、MEK 和 PD-L1 的三重阻断在具有 MAPK 信号传导组成性激活和 PD-L1 过表达的结直肠癌模型中具有抗肿瘤活性

S Napolitano, N Matrone, A L Muddassir, G Martini, A Sorokin, V De Falco, E F Giunta, D Ciardiello, E Martinelli, V Belli, M Furia, S Kopetz, F Morgillo, F Ciardiello, T Troiani

Antitumour efficacy of MEK inhibitors in human lung cancer cells and their derivatives with acquired resistance to different tyrosine kinase inhibitors

MEK 抑制剂对获得性耐药的人类肺癌细胞及其衍生物的抗肿瘤作用

F Morgillo, T Cascone, E D'Aiuto, E Martinelli, T Troiani, P Saintigny, R De Palma, J V Heymach, L Berrino, C Tuccillo, F Ciardiello