日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Polymodal K+ channel modulation contributes to dual analgesic and anti-inflammatory actions of traditional botanical medicines

多模式钾离子通道调节有助于传统植物药发挥镇痛和抗炎的双重作用。

Rían W Manville # ,Ryan F Yoshimura # ,Andriy V Yeromin ,Derk Hogenkamp ,Jennifer van der Horst ,Angel Zavala ,Sonia Chinedu ,Grey Arena ,Emma Lasky ,Mark Fisher ,Christopher R Tracy ,Shivashankar Othy ,Thomas A Jepps ,Michael D Cahalan ,Geoffrey W Abbott

Mapping bark bacteria: initial insights of stemflow-induced changes in bark surface phyla

树皮细菌图谱:茎流诱导的树皮表面门类变化的初步见解

Hudson, J E; Levia, D F; Yoshimura, K M; Gottel, N R; Hudson, S A; Biddle, J F

KCNQ and KCNE Isoform-Dependent Pharmacology Rationalizes Native American Dual Use of Specific Plants as Both Analgesics and Gastrointestinal Therapeutics

KCNQ 和 KCNE 异构体依赖性药理学合理化了美洲原住民将特定植物用作止痛药和胃肠道治疗剂的双重用途

Geoffrey W Abbott, Kaitlyn E Redford, Ryan F Yoshimura, Rían W Manville, Luiz Moreira, Kevin Tran, Grey Arena, Alexandra Kookootsedes, Emma Lasky, Elliot Gunnison

A diverse range of bacterial and eukaryotic chitinases hydrolyzes the LacNAc (Galβ1-4GlcNAc) and LacdiNAc (GalNAcβ1-4GlcNAc) motifs found on vertebrate and insect cells.

多种细菌和真核生物几丁质酶可水解脊椎动物和昆虫细胞上发现的 LacNAc (Galβ1-4GlcNAc) 和 LacdiNAc (GalNAcβ1-4GlcNAc) 基序

Frederiksen Rikki F, Yoshimura Yayoi, Storgaard Birgit G, Paspaliari Dafni K, Petersen Bent O, Chen Kowa, Larsen Tanja, Duus Jens Ø, Ingmer Hanne, Bovin Nicolai V, Westerlind Ulrika, Blixt Ola, Palcic Monica M, Leisner Jørgen J

Porphyromonas gingivalis RagB is a proinflammatory signal transducer and activator of transcription 4 agonist

牙龈卟啉单胞菌 RagB 是一种促炎信号转导剂和转录激活剂 4 激动剂

J A Hutcherson, J Bagaitkar, K Nagano, F Yoshimura, H Wang, D A Scott

Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors

一系列芳基吡啶-3-基甲酮作为 α7 烟碱乙酰胆碱受体 I 型正变构调节剂的设计、合成和活性

Derk J Hogenkamp, Thomas A Ford-Hutchinson, Wen-Yen Li, Edward R Whittemore, Ryan F Yoshimura, Minhtam B Tran, Timothy B C Johnstone, Gavin D Bascom, Hannah Rollins, Lena Lu, Kelvin W Gee

Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia

限制含有 β1 亚基的 GABAA 受体亚型的活性可减少共济失调

Kelvin W Gee, Minhtam B Tran, Derk J Hogenkamp, Timothy B Johnstone, Rudy E Bagnera, Ryan F Yoshimura, Jin-Cheng Huang, James D Belluzzi, Edward R Whittemore

Lack of inducible nitric oxide synthases attenuates leukocyte-endothelial cell interactions in retinal microcirculation

诱导型一氧化氮合酶的缺乏会减弱视网膜微循环中白细胞与内皮细胞的相互作用。

Iwama, D; Miyahara, S; Tamura, H; Miyamoto, K; Hirose, F; Yoshimura, N

Amino acid insertions near Gag cleavage sites restore the otherwise compromised replication of human immunodeficiency virus type 1 variants resistant to protease inhibitors

在 Gag 切割位点附近插入氨基酸可以恢复对蛋白酶抑制剂具有抗性的 1 型人类免疫缺陷病毒变异株原本受损的复制能力。

Tamiya, Sadahiro; Mardy, Sek; Kavlick, Mark F; Yoshimura, Kazuhisa; Mistuya, Hiroaki