日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Bioengineered extracellular vesicles escape lysosomal degradation and deliver Tet-PKM2 for macrophage immunometabolic reprogramming and periodontitis treatment.

生物工程改造的细胞外囊泡可逃避溶酶体降解，并将 Tet-PKM2 递送至巨噬细胞进行免疫代谢重编程，用于治疗牙周炎。

期刊:Bioactive Materials
影响因子:20.3
doi:10.1016/j.bioactmat.2026.01.002
Zhang Wen-Jie, Tian Bei-Min, Li Fang, Li Xuan, Wu Rui-Xin, Yin Yuan, Wang Jia, Deng Dao-Kun, Chen Yu-Zhe, Wang Hong-Yu, Du Yu-Xuan, Wang Xuan, Xiao Yin, He Xiao-Tao, Chen Fa-Ming
细胞生物学
巨噬细胞
免疫代谢
巨噬细胞
囊泡
代谢重编程
发表日期：2026
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TCF21 promotes epithelial-to-mesenchymal transition and cytoskeleton reorganization in uterine development and endometriosis

TCF21促进子宫发育和子宫内膜异位症中的上皮间质转化和细胞骨架重组

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69551-5
Zhu, Jingwen; Wu, Peili; Ma, Yilei; Peng, Zijun; Fa, Hangwei; Qin, Leyi; Geng, Mengyang; Lu, Ruihui; Zeng, Cheng; Wu, Ning; Zhang, Deyu; Zhang, Chengying; Peng, Chao; Zhou, Yingfang; Shang, Yongfeng; Liang, Jing; Xue, Qing
细胞生物学
发育与干细胞
上皮间质转化
发表日期：2026
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Stenotrophomonas promotes gastrointestinal tumor progression via STING degradation in tumour cells and mitigated immune response.

嗜麦芽窄食单胞菌通过降解肿瘤细胞中的 STING 和减弱免疫反应来促进胃肠道肿瘤的进展。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68649-0
Feng Huolun, Chen Kunling, Xi Zhihui, Xia Baijin, Chen Xi, Huang Yiqin, Huang Zuda, Guo Jieqing, Zhu Dandan, Ling Fa, Zhou Jianlong, Zhang Yuhan, Zhang Yucheng, Liu Yongfeng, Zhang Wenxing, Lin Jiatong, Lyu Zejian, Huang Qunsheng, Wang Junjiang, Hou Tieying, Zheng Jiabin, Xing Fan, Li Yong
肿瘤
肿瘤免疫
STING
细胞生物学
肿瘤细胞
免疫/内分泌
发表日期：2026
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vEMRec: High-Resolution Volume Electron Microscopy Reconstruction Based on Structure-Preserving and High-Fidelity 3D Alignment

vEMRec：基于结构保持和高保真3D对齐的高分辨率体电子显微镜重建

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202519098
Zhang, Zhenbang; Li, Hongjia; Yang, Zhongjun; Xu, Zhiqiang; Sun, Duanchen; Gao, Xin; Zhang, Fa; Han, Renmin
3D/类器官
发表日期：2026
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Amelioration of Post-Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

通过靶向抑制AQP4改善卒中后水肿和微循环功能障碍，同时保护淋巴系统

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202520118
Jin, Lei; Yang, Zeyu; Wei, Boyang; Wu, Yu; Li, Longxiang; Zhou, Jiaming; Zhang, Xin; Jin, Fa; Su, Shixing; Liu, Yanchao; Li, Ran; Guo, Shenquan; Liu, Xingwu; Cai, Yu; Liu, Hong; Chen, Min; Liu, Wenchao; Duan, Chuanzhi; Li, Xifeng
AQP4
心血管
发表日期：2026
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Targeting the Notch1-YY1-ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8(+) T-Cell-Driven Cancer Cell Pyroptosis.

靶向 Notch1-YY1-ICAM1 信号轴可激活 CD8(+) T 细胞驱动的癌细胞焦亡，从而增强免疫疗法在 HCC 中的疗效。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202512845
Zhu Ke, Zhang Fa-Peng, Qin Chao, Song Zhi-Xiao, Yang Cai-Ni, Lin Shu-Sheng, Yu Xian-Huan, Wu Wen-Rui, Liu Chao-Qun, Liu Chao, Xu Lei-Bo
肿瘤
表观遗传
T细胞
肿瘤免疫
Notch
信号转导
ICAM1
CD8
Notch1
焦亡
YY1
细胞生物学
免疫/内分泌
发表日期：2026
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Tissue-type Differences in Focused Ultrasound and Microbubble-mediated Drug Delivery to the Brain Exist at Vessel Level

聚焦超声和微泡介导的药物递送至大脑的组织类型差异存在于血管水平

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.117691
De Maio, Alessandro; Lin, Fa-Hsuan; Stefanovic, Bojana; O'Reilly, Meaghan A
神经科学
发表日期：2026
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PE-STAR: prime editing with SOS-triggered and RecJ-augmented repair enables high-efficiency editing in Escherichia coli

PE-STAR：利用 SOS 触发和 RecJ 增强的修复机制进行先导编辑，可在大肠杆菌中实现高效编辑。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkag285
Duan, Xiaoyan; Zhang, Haonan; Lv, Jiugong; Fan, Xiangrui; Liu, Xiaohang; Wang, Qingqing; Zhang, Fa; Zhang, Qiang; Liu, Lin; Liang, Liya; Liu, Rongming
STAR
发表日期：2026
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SARS-CoV-2 damages cardiomyocyte mitochondria and implicates long COVID-associated cardiovascular manifestations

SARS-CoV-2 会损害心肌细胞线粒体，并导致新冠长期相关心血管症状。

期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2025.05.013
Che, Wenliang; Guo, Shuai; Wang, Yanqun; Wan, Xiaohua; Tan, Bingyu; Li, Hailing; Alifu, Jiasuer; Zhu, Mengyun; Chen, Zesong; Li, Peiyao; Zhang, Lei; Zhang, Zhaoyong; Wang, Yiliang; Huang, Xiaohan; Wang, Xinsheng; Zhu, Jian; Pan, Xijiang; Zhang, Fa; Wang, Peiyi; Sui, Sen-Fang; Zhao, Jincun; Xu, Yawei; Liu, Zheng
SARS-CoV-2
新冠
微生物学
线粒体
细胞生物学
发表日期：2026
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Association of the C-reactive protein-triglyceride-glucose index with metabolic dysfunction-associated steatotic liver disease and long-term all-cause and cardiovascular mortality: evidence from two nationwide prospective cohort studies

C反应蛋白-甘油三酯-葡萄糖指数与代谢功能障碍相关脂肪肝疾病及长期全因死亡率和心血管死亡率的关联：来自两项全国性前瞻性队列研究的证据

期刊:Cardiovascular Diabetology
影响因子:10.6
doi:10.1186/s12933-026-03119-x
Jin, Xue-Feng; Su, Zhao-Jie; Zhong, Jian-Fa; Wang, Jie; Shi, Bao-Jie; Liu, Zhen-Yu; Li, Ping-Sui; Xiong, Xing; Xu, Shi-Quan; Qiu, Cheng; Xiao, Yi; Li, Si-Bo; Tong, Wen-Hui; Ge, Jing-Ping; Li, Hang-Xu; Liu, Xiao-Yan; Li, Zi-Zhi; Kong, Xiang-Rui; Chen, Jun-Lin; Wen, Xue-Jiao; Sun, Pan; Chen, Peng-Peng; Li, Yang-Yang; Chen, Yang; Mao, Lan-Tian; Peng, Zhi-Hai; Li, Hao; Zhang, Tong
脂肪肝
代谢
发表日期：2026
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