日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

WWC proteins-mediated compensatory mechanism restricts schwannomatosis driven by NF2 loss of function

WWC 蛋白介导的补偿机制可限制由 NF2 功能丧失引起的神经鞘瘤病

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.adp4765
Xueying Wang, Rui Zhu, Pengcheng Yu, Sixian Qi, Zhenxing Zhong, Ruxin Jin, Yu Wang, Yuan Gu, Dan Ye, Kang Chen, Yilai Shu, Yi Wang, Fa-Xing Yu
神经
Human
HSP90
发表日期：2025
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Proteasome stress activates YAP/TAZ through the RAP2-MAP4Ks-LATS1/2 pathway and its therapeutic implications in solid tumors

蛋白酶体应激通过 RAP2-MAP4Ks-LATS1/2 通路激活 YAP/TAZ，及其在实体瘤治疗中的意义

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2517376122
Wang, Xin; Gu, Yuan; Zhong, Zhenxing; Yu, Pengcheng; Liu, Wenshuai; Zhu, Rui; Wang, Yu; Zhou, Zhaocai; Sun, Yihong; Wang, Xuefei; Yu, Fa-Xing
TAZ
信号转导
MAP4
LATS1
LAT
ATS1
YAP
发表日期：2025
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Flexural Behavior of Desert Sand Concrete-Filled Steel Tube: Experimental Validation, FEM Analysis, and Design Formulas

沙漠砂混凝土填充钢管的抗弯性能：实验验证、有限元分析和设计公式

期刊:Materials
影响因子:3.2
doi:10.3390/ma18102371
Zhang, Chao-Cheng; Ding, Fa-Xing; Sadat, Said Ikram; Lyu, Fei; Huang, Xin-Yu; Gao, Rui; Yu, Tao; Liu, Yu-Lin
发表日期：2025
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Gene therapy for diffuse pleural mesotheliomas in preclinical models by concurrent expression of NF2 and SuperHippo

在临床前模型中，通过同时表达NF2和SuperHippo基因治疗弥漫性胸膜间皮瘤

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2024.101763
Rui Zhu,Xincheng Liu,Xu Zhang,Zhenxing Zhong,Sixian Qi,Ruxin Jin,Yuan Gu,Yu Wang,Chen Ling,Kang Chen,Dan Ye,Fa-Xing Yu
Hippo
发表日期：2024
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JCAD deficiency delayed liver regenerative repair through the Hippo-YAP signalling pathway

JCAD 缺乏通过 Hippo-YAP 信号通路延迟肝脏再生修复

期刊:Clinical and Translational Medicine
影响因子:7.9
doi:10.1002/ctm2.1630
Li Zhang, Yong-Yu Yang, Li Xie, Yuan Zhou, Zhenxing Zhong, Jia Ding, Zhong-Hua Wang, Yu-Li Wang, Xiu-Ping Liu, Fa-Xing Yu, Jian Wu
信号转导
Hippo
发表日期：2024
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Phosphorylation of NF2 at Serine-13 by MAP4K family kinases mediates pathological angiogenesis

MAP4K家族激酶对NF2丝氨酸13位点的磷酸化介导病理性血管生成

期刊:Protein & Cell
影响因子:12.8
doi:10.1093/procel/pwac005
Ma, Mingyue; Zhong, Zhenxing; Zhu, Yuwen; Gu, Yuan; Jin, Ruxin; Meng, Zhipeng; Wang, Yu; Yu, Fa-Xing
信号转导
MAP4
磷酸化
血管生成
发表日期：2023
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TERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis

TERT 通过调节核糖体生物合成加速 BRAF 突变诱导的甲状腺癌去分化和进展

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.adg7125
Pengcheng Yu, Ning Qu, Rui Zhu, Jiaqian Hu, Peizhen Han, Jiahao Wu, Licheng Tan, Hualei Gan, Cong He, Chuantao Fang, Yubin Lei, Jian Li, Chenxi He, Fei Lan, Xiao Shi, Wenjun Wei, Yu Wang, Qinghai Ji, Fa-Xing Yu, Yu-Long Wang
肿瘤
甲状腺癌
发表日期：2023
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Proteolytic activation of angiomotin by DDI2 promotes angiogenesis

DDI2 蛋白水解激活血管动蛋白促进血管生成

期刊:EMBO Journal
影响因子:9.4
doi:10.15252/embj.2022112900
Yu Wang #, Yuwen Zhu #, Yebin Wang, Yue Chang, Fang Geng, Mingyue Ma, Yuan Gu, Aijuan Yu, Rui Zhu, Pengcheng Yu, Zhao Sha, Sixian Qi, Jian Li, Wencao Zhao, Weijun Pan, Ruilin Zhang, Fa-Xing Yu
信号转导
IP
WB
Human
Angiomotin
发表日期：2023
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WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT

WWC1/2 通过稳定 AMOT 来调节小鼠的脊柱形成和认知功能。

期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/s41419-023-06020-7
Runyi Cao # ,Rui Zhu # ,Zhao Sha ,Sixian Qi ,Zhenxing Zhong ,Fengyun Zheng ,Yubin Lei ,Yanfeng Tan ,Yuwen Zhu ,Yu Wang ,Yi Wang ,Fa-Xing Yu
AMOT
神经科学
发表日期：2023
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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

WWC 蛋白介导 Hippo 激酶激活 LATS1/2 并暗示一种肿瘤抑制策略

期刊:Molecular Cell
影响因子:14.5
doi:10.1016/j.molcel.2022.03.027
Sixian Qi, Yuwen Zhu, Xincheng Liu, Pengyue Li, Yebin Wang, Yan Zeng, Aijuan Yu, Yu Wang, Zhao Sha, Zhenxing Zhong, Rui Zhu, Haixin Yuan, Dan Ye, Shenglin Huang, Chen Ling, Yanhui Xu, Dawang Zhou, Lei Zhang, Fa-Xing Yu
信号转导
肿瘤
Hippo
发表日期：2022
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