日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapid synthesis of glycosylated insulins by flow-based peptide synthesis

利用流动肽合成法快速合成糖基化胰岛素

Maki, Yuta; Mong, Surin K; Chandrashekar, Chaitra; Forbes, Briony E; Hossain, Mohammed Akhter; Yamaguchi, Shintaro; Fadzen, Colin M; Kajihara, Yasuhiro; Pentelute, Bradley L

A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood-Brain Barrier Permeability and Targets Glioblastoma

一种肿瘤靶向肽平台可提高药物溶解度,改善血脑屏障通透性并靶向胶质母细胞瘤。

Cho, Choi-Fong; Farquhar, Charlotte E; Fadzen, Colin M; Scott, Benjamin; Zhuang, Pei; von Spreckelsen, Niklas; Loas, Andrei; Hartrampf, Nina; Pentelute, Bradley L; Lawler, Sean E

Deep learning to design nuclear-targeting abiotic miniproteins

利用深度学习设计靶向核的非生物微型蛋白

Schissel, Carly K; Mohapatra, Somesh; Wolfe, Justin M; Fadzen, Colin M; Bellovoda, Kamela; Wu, Chia-Ling; Wood, Jenna A; Malmberg, Annika B; Loas, Andrei; Gómez-Bombarelli, Rafael; Pentelute, Bradley L

Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican

利用一种新型肽靶向治疗胶质母细胞瘤,该肽特异性识别brevican的去糖基化异构体。

von Spreckelsen, Niklas; Fadzen, Colin M; Hartrampf, Nina; Ghotmi, Yarah; Wolfe, Justin M; Dubey, Shipra; Yang, Bo Yeun; Kijewski, Marie F; Wang, Shuyan; Farquhar, Charlotte; Bergmann, Sonja; Zdioruk, Mykola; Wasserburg, J Roscoe; Scott, Benjamin; Murrell, Emily; Bononi, Fernanda C; Luyt, Leonard G; DiCarli, Marcelo; Lamfers, Martine L M; Ligon, Keith L; Chiocca, E Antonio; Viapiano, Mariano S; Pentelute, Bradley L; Lawler, Sean E; Cho, Choi-Fong

A Platinum(IV) Prodrug-Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain

铂(IV)前药-全氟芳基大环肽结合物增强大脑对铂的吸收

Colin M Fadzen, Justin M Wolfe, Wen Zhou, Choi-Fong Cho, Niklas von Spreckelsen, Kathryn T Hutchinson, Yen-Chun Lee, E Antonio Chiocca, Sean E Lawler, Omer H Yilmaz, Stephen J Lippard, Bradley L Pentelute

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

一种利用多肽和蛋白质对复杂小分子进行后期功能化的化学选择性策略

Cohen, Daniel T; Zhang, Chi; Fadzen, Colin M; Mijalis, Alexander J; Hie, Liana; Johnson, Kenneth D; Shriver, Zachary; Plante, Obadiah; Miller, Scott J; Buchwald, Stephen L; Pentelute, Bradley L

Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides

用于递送反义寡核苷酸的全氟芳基双环细胞穿透肽

Wolfe, Justin M; Fadzen, Colin M; Holden, Rebecca L; Yao, Monica; Hanson, Gunnar J; Pentelute, Bradley L

Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics

血脑屏障类器官用于研究中枢神经系统治疗的渗透性

Sonja Bergmann, Sean E Lawler, Yuan Qu, Colin M Fadzen, Justin M Wolfe, Michael S Regan, Bradley L Pentelute, Nathalie Y R Agar, Choi-Fong Cho

Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery

利用机器学习预测用于反义递送的细胞穿透肽

Wolfe, Justin M; Fadzen, Colin M; Choo, Zi-Ning; Holden, Rebecca L; Yao, Monica; Hanson, Gunnar J; Pentelute, Bradley L

Perfluoroarene-Based Peptide Macrocycles to Enhance Penetration Across the Blood-Brain Barrier

基于全氟芳烃的肽大环增强其穿过血脑屏障的能力

Fadzen, Colin M; Wolfe, Justin M; Cho, Choi-Fong; Chiocca, E Antonio; Lawler, Sean E; Pentelute, Bradley L