日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Effect on preoperative anxiety of a personalized three-dimensional kidney model prior to nephron-sparing surgery for renal tumor: study protocol for a randomized controlled trial (Rein 3D Print-Anxiety - UroCCR 113)

个性化三维肾脏模型对肾肿瘤肾单位保留手术前焦虑的影响：一项随机对照试验的研究方案（Rein 3D Print-Anxiety - UroCCR 113）

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0321747
Pitout, Alice; Margue, Gaëlle; Sarrazin, Joffrey; Richert, Laura; Larribère, Hugo; Masanet, Sarah; Waeckel, Thibaut; Bigot, Pierre; Boissier, Romain; Parier, Bastien; De Vergie, Stéphane; Jaffredo, Manon; Ricard, Solène; Hoarau, Hélène; Jutand, Marthe-Aline; Faessel, Matthieu; Sabatier, Jocelyn; Bernhard, Jean-Christophe
3D/类器官
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Effects of a personalized or generic three-dimensional tumoral kidney model on patient experience and caregiver-patient interactions, before and after partial nephrectomy, a randomized trial (Rein 3D Print Personalize-UroCCR 114)

个性化或通用三维肿瘤肾脏模型对患者体验和护理人员与患者互动的影响，在部分肾切除术前后，一项随机试验（Rein 3D Print Personalize-UroCCR 114）

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0323515
Pattou, Maxime; Masanet, Sarah; Jutand, Marthe-Aline; Hoarau, Hélène; Sarrazin, Joffrey; Pitout, Alice; Richert, Laura; Larribere, Hugo; Rubat Baleuri, Federico; Jaffredo, Manon; Ricard, Solène; Faessel, Matthieu; Sabatier, Jocelyn; Bernhard, Jean-Christophe; Margue, Gaëlle
3D/类器官
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Safety and pharmacodynamics of a single infusion of danavorexton in adults with idiopathic hypersomnia

单次输注达那沃雷克斯顿治疗成人特发性嗜睡症的安全性和药效学

期刊:Sleep
影响因子:4.9
doi:10.1093/sleep/zsad049
Mignot, Emmanuel; Bogan, Richard K; Emsellem, Helene; Foldvary-Schaefer, Nancy; Naylor, Melissa; Neuwirth, Rachel; Faessel, Hélène; Swick, Todd; Olsson, Tina
发表日期：2023
文献求助 收藏

Pevonedistat in East Asian patients with acute myeloid leukemia or myelodysplastic syndromes: a phase 1/1b study to evaluate safety, pharmacokinetics and activity as a single agent and in combination with azacitidine

在东亚急性髓系白血病或骨髓增生异常综合征患者中评估培沃地司他单药及联合阿扎胞苷治疗的安全性、药代动力学和活性的1/1b期研究

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-022-01264-w
Handa, Hiroshi; Cheong, June-Won; Onishi, Yasushi; Iida, Hiroatsu; Kobayashi, Yukio; Kim, Hyeoung-Joon; Chiou, Tzeon-Jye; Izutsu, Koji; Tsukurov, Olga; Zhou, Xiaofei; Faessel, Helene; Yuan, Ying; Sedarati, Farhad; Faller, Douglas V; Kimura, Akiko; Wu, Shang-Ju
白血病
发表日期：2022
文献求助 收藏

Orexin 2 receptor-selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients

选择性食欲素2受体激动剂达那沃雷克顿可改善小鼠模型和人类患者的发作性睡病表型。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2207531119
Evans, Rebecca; Kimura, Haruhide; Alexander, Robert; Davies, Ceri H; Faessel, Hélène; Hartman, Deborah S; Ishikawa, Takashi; Ratti, Emiliangelo; Shimizu, Kohei; Suzuki, Motohisa; Tanaka, Shinichiro; Yukitake, Hiroshi; Dauvilliers, Yves; Mignot, Emmanuel
信号转导
发表日期：2022
文献求助 收藏

Safety, tolerability, pharmacokinetics, pharmacodynamics, bioavailability and food effect of single doses of soticlestat in healthy subjects

在健康受试者中单次服用索替克司他后的安全性、耐受性、药代动力学、药效学、生物利用度和食物效应

期刊:British Journal of Clinical Pharmacology
影响因子:3
doi:10.1111/bcp.14854
Wang, Shining; Chen, Grace; Merlo Pich, Emilio; Affinito, John; Cwik, Michael; Faessel, Hélène
发表日期：2021
文献求助 收藏

Phase I study assessing the mass balance, pharmacokinetics, and excretion of [(14)C]-pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumors

一项评估[(14)C]-pevonedistat（一种NEDD8激活酶抑制剂）在晚期实体瘤患者中的质量平衡、药代动力学和排泄情况的I期研究

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-020-01017-x
Zhou, Xiaofei; Sedarati, Farhad; Faller, Douglas V; Zhao, Dan; Faessel, Hélène M; Chowdhury, Swapan; Bolleddula, Jayaprakasam; Li, Yuexian; Venkatakrishnan, Karthik; Papai, Zsuzsanna
发表日期：2021
文献求助 收藏

Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumors

一项针对晚期实体瘤患者的Ib期研究，评估了NEDD8激活酶抑制剂pevonedistat联合多西他赛、卡铂和紫杉醇或吉西他滨的疗效。

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-018-0610-0
Lockhart, A Craig; Bauer, Todd M; Aggarwal, Charu; Lee, Carrie B; Harvey, R Donald; Cohen, Roger B; Sedarati, Farhad; Nip, Tsz Keung; Faessel, Hélène; Dash, Ajeeta B; Dezube, Bruce J; Faller, Douglas V; Dowlati, Afshin
发表日期：2019
文献求助 收藏

Expanded safety analysis of pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukemia and myelodysplastic syndromes

对首创的NEDD8激活酶抑制剂pevonedistat在急性髓系白血病和骨髓增生异常综合征患者中的安全性进行了扩展分析

期刊:Blood Cancer Journal
影响因子:11.6
doi:10.1038/bcj.2017.1
Swords, R T; Watts, J; Erba, H P; Altman, J K; Maris, M; Anwer, F; Hua, Z; Stein, H; Faessel, H; Sedarati, F; Dezube, B J; Giles, F J; Medeiros, B C; DeAngelo, D J
白血病
发表日期：2017
文献求助 收藏

Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma

一项针对复发/难治性多发性骨髓瘤或淋巴瘤患者的新型在研NEDD8激活酶抑制剂Pevonedistat（MLN4924）的I期研究

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-15-1237
Shah, Jatin J; Jakubowiak, Andrzej J; O'Connor, Owen A; Orlowski, Robert Z; Harvey, R Donald; Smith, Mitchell R; Lebovic, Daniel; Diefenbach, Catherine; Kelly, Kevin; Hua, Zhaowei; Berger, Allison J; Mulligan, George; Faessel, Hélène M; Tirrell, Stephen; Dezube, Bruce J; Lonial, Sagar
淋巴瘤
骨髓瘤
多发性骨髓瘤
发表日期：2016
文献求助 收藏