文献库，生知库 | 链接生命科学的每一步

Jousse, Céline; Parry, Laurent; Cueff, Gwendal; Brandolini-Bunlon, Marion; Tournayre, Jérémy; Bruhat, Alain; Maurin, Anne-Catherine; Vituret, Cyrielle; Averous, Julien; Muranishi, Yuki; Fafournoux, Pierre

肥胖

代谢

发表日期：2025

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Pre-cachectic changes in amino acid homeostasis precede activation of eIF2Î± signaling in the liver at the onset of C26 cancer-induced cachexia.

在 C26 癌症引起的恶病质发作时，肝脏中 eIF2α 信号传导的激活之前，氨基酸稳态的恶病质前期变化就已经发生

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.112030

Chaouki Ghita, Parry Laurent, Vituret Cyrielle, Jousse CÃ©line, Leremboure Martin, Bourgne CÃ©line, Mosoni Laurent, Delorme Yoann, Djelloul-Mazouz Mehdi, Hermet Julien, Averous Julien, Bruhat Alain, Combaret Lydie, Taillandier Daniel, Papet Isabelle, Bindels Laure B, Fafournoux Pierre, Maurin Anne-Catherine

Dynamics of Leptospirosis Transmission Within Urban Norway Rat (Rattus norvegicus) Populations in Densely Populated French Areas: Implications for Public Health

法国人口密集地区城市挪威褐鼠（Rattus norvegicus）种群中钩端螺旋体病传播动态：对公共卫生的启示

期刊:Transboundary and Emerging Diseases

影响因子:3

doi:10.1155/tbed/3451406

Soro, Sionfoungo; Groud, Karine; Fafournoux, Ambre; Monchatre-Leroy, Elodie; Kodjo, Angeli; Lefebvre, Sébastien; Chatron, Nolan; Lattard, Virginie

发表日期：2025

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Infectious potential and circulation of SARS-CoV-2 in wild rats

SARS-CoV-2在野生鼠类中的传染性和传播

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0316882

Beissat, Kevyn; Lattard, Virginie; Picard-Meyer, Evelyne; Fafournoux, Ambre; Soro, Sionfoungo Daouda; Servat, Alexandre; Vincent-Hubert, Françoise; Boué, Franck; Chatron, Nolan; Monchâtre-Leroy, Elodie; Wasniewski, Marine

SARS-CoV-2

发表日期：2025

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Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair

MuRF1-UBE2复合物的结构预测揭示了决定每对MuRF1-E2相互作用选择性的氨基酸残基。

期刊:

影响因子:

doi:10.1111/febs.70017

Claustre, Agnès; Malige, Mélodie; Macheton, Maëlys; Combaret, Lydie; Lefai, Etienne; Fafournoux, Pierre; Taillandier, Daniel; Henri, Julien; Polge, Cécile

发表日期：2025

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Knockout of the Muscle-Specific E3 Ligase MuRF1 Affects Liver Lipid Metabolism upon Dexamethasone Treatment in Mice

敲除肌肉特异性E3连接酶MuRF1会影响地塞米松治疗小鼠的肝脏脂质代谢

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.4c08501

Mosoni, Laurent; Germond, Arno; Coudy-Gandilhon, Cécile; Malige, Mélodie; Claustre, Agnès; Delabrise, Coralie; Djelloul-Mazouz, Mehdi; Delorme, Yoann; Hermet, Julien; Fafournoux, Pierre; Combaret, Lydie; Polge, Cécile; Maurin, Anne-Catherine; Taillandier, Daniel

代谢

发表日期：2024

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Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears

在接受氟吉诺酮治疗的小鼠和冬眠棕熊中，ATF4 调节的 Atrogenes 的诱导与废用期间的肌肉萎缩无关

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms24010621

Laura Cussonneau, Cécile Coudy-Gandilhon, Christiane Deval, Ghita Chaouki, Mehdi Djelloul-Mazouz, Yoann Delorme, Julien Hermet, Guillemette Gauquelin-Koch, Cécile Polge, Daniel Taillandier, Julien Averous, Alain Bruhat, Céline Jousse, Isabelle Papet, Fabrice Bertile, Etienne Lefai, Pierre Fafournoux

Activation of the eIF2α-ATF4 Pathway by Chronic Paracetamol Treatment Is Prevented by Dietary Supplementation with Cysteine

膳食补充半胱氨酸可预防长期服用对乙酰氨基酚激活 eIF2α-ATF4 通路

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms23137196

Valérie Carraro, Lydie Combaret, Cécile Coudy-Gandilhon, Laurent Parry, Julien Averous, Anne-Catherine Maurin, Céline Jousse, Guillaume Voyard, Pierre Fafournoux, Isabelle Papet, Alain Bruhat

其它

发表日期：2022

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GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid.

GCN2 在短期内缺乏单一必需氨基酸时会上调自噬

期刊:Autophagy Reports

影响因子:

doi:10.1080/27694127.2022.2049045

Maurin Anne-Catherine, Parry Laurent, B'chir Wafa, Carraro ValÃ©rie, Coudy-Gandilhon CÃ©cile, Chaouki Ghita, Chaveroux CÃ©dric, Mordier Sylvie, Martinie Brigitte, Reinhardt Vanessa, Jousse CÃ©line, Bruhat Alain, Codogno Patrice, Averous Julien, Fafournoux Pierre

UBE2L3, a Partner of MuRF1/TRIM63, Is Involved in the Degradation of Myofibrillar Actin and Myosin

UBE2L3 是 MuRF1/TRIM63 的伴侣，参与肌原纤维肌动蛋白和肌球蛋白的降解

期刊:Cells

影响因子:5.1

doi:10.3390/cells10081974

Dulce Peris-Moreno, Mélodie Malige, Agnès Claustre, Andrea Armani, Cécile Coudy-Gandilhon, Christiane Deval, Daniel Béchet, Pierre Fafournoux, Marco Sandri, Lydie Combaret, Daniel Taillandier, Cécile Polge

信号转导

发表日期：2021

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Identification of a specific set of genes predicting obesity before phenotype appearance

在表型出现之前，鉴定出一组能够预测肥胖的特定基因。

Pre-cachectic changes in amino acid homeostasis precede activation of eIF2Î± signaling in the liver at the onset of C26 cancer-induced cachexia.

在 C26 癌症引起的恶病质发作时，肝脏中 eIF2α 信号传导的激活之前，氨基酸稳态的恶病质前期变化就已经发生

Dynamics of Leptospirosis Transmission Within Urban Norway Rat (Rattus norvegicus) Populations in Densely Populated French Areas: Implications for Public Health

法国人口密集地区城市挪威褐鼠（Rattus norvegicus）种群中钩端螺旋体病传播动态：对公共卫生的启示

Infectious potential and circulation of SARS-CoV-2 in wild rats

SARS-CoV-2在野生鼠类中的传染性和传播

Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair

MuRF1-UBE2复合物的结构预测揭示了决定每对MuRF1-E2相互作用选择性的氨基酸残基。

Knockout of the Muscle-Specific E3 Ligase MuRF1 Affects Liver Lipid Metabolism upon Dexamethasone Treatment in Mice

敲除肌肉特异性E3连接酶MuRF1会影响地塞米松治疗小鼠的肝脏脂质代谢

Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears

在接受氟吉诺酮治疗的小鼠和冬眠棕熊中，ATF4 调节的 Atrogenes 的诱导与废用期间的肌肉萎缩无关

Activation of the eIF2α-ATF4 Pathway by Chronic Paracetamol Treatment Is Prevented by Dietary Supplementation with Cysteine

膳食补充半胱氨酸可预防长期服用对乙酰氨基酚激活 eIF2α-ATF4 通路

GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid.

GCN2 在短期内缺乏单一必需氨基酸时会上调自噬

UBE2L3, a Partner of MuRF1/TRIM63, Is Involved in the Degradation of Myofibrillar Actin and Myosin

UBE2L3 是 MuRF1/TRIM63 的伴侣，参与肌原纤维肌动蛋白和肌球蛋白的降解