日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular mechanism of bacteriophage contraction structure of an S-layer-penetrating bacteriophage

S层穿透噬菌体的噬菌体收缩结构的分子机制

Wilson, Jason S; Fortier, Louis-Charles; Fagan, Robert P; Bullough, Per A

Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits

鉴定艰难梭菌中导致高水平万古霉素耐药性的途径,这些途径会给关键致病性状带来高适应性代价。

Buddle, Jessica E; Thompson, Lucy M; Williams, Anne S; Wright, Rosanna C T; Durham, William M; Turner, Claire E; Chaudhuri, Roy R; Brockhurst, Michael A; Fagan, Robert P

Clostridioides difficile canonical L,D-transpeptidases catalyze a novel type of peptidoglycan cross-links and are not required for beta-lactam resistance

艰难梭菌的经典L,D-转肽酶催化一种新型肽聚糖交联,且并非β-内酰胺类抗生素耐药所必需。

Galley, Nicola F; Greetham, Darren; Alamán-Zárate, Marcel G; Williamson, Mike P; Evans, Caroline A; Spittal, William D; Buddle, Jessica E; Freeman, Jane; Davis, Georgina L; Dickman, Mark J; Wilcox, Mark H; Lovering, Andrew L; Fagan, Robert P; Mesnage, Stéphane

Pathogenicity and virulence of Clostridioides difficile

艰难梭菌的致病性和毒力

Buddle, Jessica E; Fagan, Robert P

Clostridioides difficile S-Layer Protein A (SlpA) Serves as a General Phage Receptor

艰难梭菌S层蛋白A(SlpA)作为通用噬菌体受体

Royer, Alexia L M; Umansky, Andrew A; Allen, Marie-Maude; Garneau, Julian R; Ospina-Bedoya, Maicol; Kirk, Joseph A; Govoni, Gregory; Fagan, Robert P; Soutourina, Olga; Fortier, Louis-Charles

An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium

以RNA为中心的艰难梭菌全局分析揭示了Hfq在一种具有重要临床意义的革兰氏阳性菌中的广泛活性

Fuchs, Manuela; Lamm-Schmidt, Vanessa; Sulzer, Johannes; Ponath, Falk; Jenniches, Laura; Kirk, Joseph A; Fagan, Robert P; Barquist, Lars; Vogel, Jörg; Faber, Franziska

A cortex-specific penicillin-binding protein contributes to heat resistance in Clostridioides difficile spores

皮层特异性青霉素结合蛋白有助于艰难梭菌孢子产生耐热性

Alabdali, Yasir Adil Jabbar; Oatley, Peter; Kirk, Joseph A; Fagan, Robert P

Spatial organization of Clostridium difficile S-layer biogenesis.

艰难梭菌S层生物发生的空间组织

Oatley Peter, Kirk Joseph A, Ma Shuwen, Jones Simon, Fagan Robert P

New class of precision antimicrobials redefines role of Clostridium difficile S-layer in virulence and viability

新型精准抗菌药物重新定义了艰难梭菌S层在毒力和存活率中的作用

Kirk, Joseph A; Gebhart, Dana; Buckley, Anthony M; Lok, Stephen; Scholl, Dean; Douce, Gillian R; Govoni, Gregory R; Fagan, Robert P

Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains

照亮艰难梭菌:利用荧光 Lov 结构域报告基因表达

Buckley, Anthony M; Jukes, Caitlin; Candlish, Denise; Irvine, June J; Spencer, Janice; Fagan, Robert P; Roe, Andrew J; Christie, John M; Fairweather, Neil F; Douce, Gillian R