日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutant Calreticulin in MPN: Mechanistic Insights and Therapeutic Implications

MPN中的突变钙网蛋白:机制见解和治疗意义

Faiz, Mifra; Riedemann, Merle; Jutzi, Jonas S; Mullally, Ann

CALR Type 1-Like Mutations Increase Endoplasmic Reticulum Free Ca(2+) and Induce ERK1/2 Activation Independent of Thrombopoietin Receptor Activation

CALR 1型样突变增加内质网游离Ca(2+)并诱导ERK1/2激活,该过程独立于血小板生成素受体激活。

Faiz, Mifra; Dunstan-Harrison, Caitlin; Ledgerwood, Elizabeth C

Megakaryocyte maturation involves activation of the adaptive unfolded protein response.

巨核细胞成熟涉及适应性未折叠蛋白反应的激活

Faiz Mifra, Kalev-Zylinska Maggie L, Dunstan-Harrison Caitlin, Singleton Dean C, Hay Michael P, Ledgerwood Elizabeth C