日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Elexacaftor/Tezacaftor/Ivacaftor for Cystic Fibrosis and Rare CFTR Variants: In Vitro Translation to a Phase 3, Double-Blind, Randomized, Placebo-controlled Trial and Real-World Study

Elexacaftor/Tezacaftor/Ivacaftor 用于囊性纤维化和罕见 CFTR 变异:体外研究向 3 期双盲、随机、安慰剂对照试验和真实世界研究的转化

Castellani, Carlo; Mondejar-Lopez, Pedro; Van Goor, Fredrick; Quon, Bradley S; Alghisi, Federico; Fabrizzi, Benedetta; Ramsey, Bonnie; Taylor-Cousar, Jennifer L; McKone, Edward F; Tullis, Elizabeth; Weinstock, Tanya G; Tan, Vincent; Ahluwalia, Neil; Mahic, Milada; Liu, Lingyun; Saayman, Sheena; Altshuler, David; Waltz, David; Mall, Marcus A; Fajac, Isabelle

The clinical, psychosocial, and economic burden of cystic fibrosis lung disease in the era of CFTR modulator therapy

囊性纤维化肺病在CFTR调节剂治疗时代所面临的临床、心理社会和经济负担

Fajac, Isabelle; Jain, Raksha; Mall, Marcus A; Rubin, Bruce K; Flume, Patrick A

Cystic Fibrosis Microbiome-directed Antibiotic Therapy Trial in Exacerbations Results Stratified (CFMATTERS): results of a multicentre randomised controlled trial

囊性纤维化急性加重期微生物组导向抗生素治疗试验结果分层分析(CFMATTERS):一项多中心随机对照试验的结果

Plant, Barry J; Einarsson, Gisli G; Deasy, Kevin F; Dahly, Darren; Singh, Pradeep K; Barry, Peter J; Goss, Christopher H; Fajac, Isabelle; Vagg, Tamara; Durieu, Isabelle; Flanagan, Evelyn; O'Callaghan, Grace; Martin, Clémence; Burgel, Pierre-Régis; Haworth, Charles S; Floto, R Andres; Downey, Damian G; Dupont, Lieven J; Jones, Andrew M; Elborn, J Stuart; Eustace, Joseph A; Mall, Marcus A; Tunney, Michael M

Oncogenic and teratogenic effects of Trp53(Y217C), an inflammation-prone mouse model of the human hotspot mutant TP53(Y220C).

Trp53(Y217C) 的致癌和致畸作用,是人类热点突变体 TP53(Y220C) 的炎症易感小鼠模型

Jaber Sara, Eldawra Eliana, Rakotopare Jeanne, Simeonova Iva, Lejour Vincent, Gabriel Marc, Cañeque Tatiana, Volochtchouk Vitalina, Licaj Monika, Fajac Anne, Rodriguez Raphaël, Morillon Antonin, Bardot Boris, Toledo Franck

Screening Mammography and Breast Cancer: Variation in Risk with Rare Deleterious or Predicted Deleterious Variants in DNA Repair Genes

乳腺癌筛查:DNA修复基因中罕见有害或预测有害变异与风险差异的关系

Ribeiro-Guerra, Maximiliano; Dondon, Marie-Gabrielle; Eon-Marchais, Séverine; Le Gal, Dorothée; Beauvallet, Juana; Mebirouk, Noura; Belotti, Muriel; Cavaciuti, Eve; Adenis-Lavignasse, Claude; Audebert-Bellanger, Séverine; Berthet, Pascaline; Bonadona, Valérie; Buecher, Bruno; Caron, Olivier; Cavaille, Mathias; Chiesa, Jean; Colas, Chrystelle; Coupier, Isabelle; Delnatte, Capucine; Dreyfus, Hélène; Fajac, Anne; Fert-Ferrer, Sandra; Fricker, Jean-Pierre; Gauthier-Villars, Marion; Gesta, Paul; Giraud, Sophie; Gladieff, Laurence; Lasset, Christine; Lejeune-Dumoulin, Sophie; Limacher, Jean-Marc; Longy, Michel; Lortholary, Alain; Luporsi, Elisabeth; Maugard, Christine M; Mortemousque, Isabelle; Nambot, Sophie; Noguès, Catherine; Pujol, Pascal; Venat-Bouvet, Laurence; Soubrier, Florent; Tinat, Julie; Tardivon, Anne; Lesueur, Fabienne; Stoppa-Lyonnet, Dominique; Andrieu, Nadine

New drugs, new challenges in cystic fibrosis care

囊性纤维化治疗领域的新药物和新挑战

Fajac, Isabelle; Burgel, Pierre-Régis; Martin, Clémence

Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas

缺乏可变剪接 p53 亚型的突变小鼠揭示 Ackr4 是 Myc 驱动的 B 细胞淋巴瘤的男性特异性预后因素

Anne Fajac, Iva Simeonova, Julia Leemput, Marc Gabriel, Aurélie Morin, Vincent Lejour, Annaïg Hamon, Jeanne Rakotopare, Wilhelm Vaysse-Zinkhöfer, Eliana Eldawra, Marina Pinskaya, Antonin Morillon, Jean-Christophe Bourdon, Boris Bardot, Franck Toledo

Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas

缺乏选择性剪接的p53亚型的突变小鼠揭示Ackr4是Myc驱动的B细胞淋巴瘤中男性特异性的预后因素

Anne Fajac ,Iva Simeonova ,Julia Leemput ,Marc Gabriel ,Aurélie Morin ,Vincent Lejour ,Annaïg Hamon ,Jeanne Rakotopare ,Wilhelm Vaysse-Zinkhöfer ,Eliana Eldawra ,Marina Pinskaya ,Antonin Morillon ,Jean-Christophe Bourdon,Boris Bardot ,Franck Toledo

Advancing the pipeline of cystic fibrosis clinical trials: a new roadmap with a global trial network perspective

推进囊性纤维化临床试验项目:基于全球试验网络视角的新路线图

Mayer-Hamblett, Nicole; Clancy, John Paul; Jain, Raksha; Donaldson, Scott H; Fajac, Isabelle; Goss, Christopher H; Polineni, Deepika; Ratjen, Felix; Quon, Bradley S; Zemanick, Edith T; Bell, Scott C; Davies, Jane C; Jain, Manu; Konstan, Michael W; Kerper, Natanya R; LaRosa, Tré; Mall, Marcus A; McKone, Edward; Pearson, Kelsie; Pilewski, Joseph M; Quittell, Lynne; Rayment, Jonathan H; Rowe, Steven M; Taylor-Cousar, Jennifer L; Retsch-Bogart, George; Downey, Damian G

Understanding and addressing the needs of people with cystic fibrosis in the era of CFTR modulator therapy

在CFTR调节剂疗法时代,了解并满足囊性纤维化患者的需求至关重要。

Hisert, Katherine B; Birket, Susan E; Clancy, John Paul; Downey, Damian G; Engelhardt, John F; Fajac, Isabelle; Gray, Robert D; Lachowicz-Scroggins, Marrah E; Mayer-Hamblett, Nicole; Thibodeau, Patrick; Tuggle, Katherine L; Wainwright, Claire E; De Boeck, Kris