日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of benzyl carbamate inhibitors of coronavirus M(pro) enzymes from a legacy collection of cysteine protease inhibitors

从一系列已知的半胱氨酸蛋白酶抑制剂中发现冠状病毒M(pro)酶的苄基氨基甲酸酯抑制剂

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2585619
Sá Magalhães Serafim, Mateus; Kronenberger, Thales; Francisco, Karol R; de Sousa Reis, Erik Vinicius; Gonçalves de Oliveira, Ellen; Marcelino E Oliveira, Fernanda Kelly; Serraglio Fortes, Isadora; Maciel Fernandes, Thaís Helena; Barbosa da Silva, Elany; Fajtova, Pavla; Skinner, Danielle E; Syed, Rafay O; Lage de Siqueira-Neto, Jair; Poso, Antti; Fernandes Mota, Bruno Eduardo; Alves Coelho-Dos-Reis, Jordana Grazziela; Santos Abrahão, Jônatas; Gonçalves Maltarollo, Vinícius; O'Donoghue, Anthony J; Caffrey, Conor R
微生物学
发表日期：2025
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Structural Insights into Salinosporamide a Mediated Inhibition of the Human 20S Proteasome.

Salinosporamide 介导的人类 20S 蛋白酶体抑制的结构见解

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30061386
Sülzen Hagen, Fajtova Pavla, O'Donoghue Anthony J, Silhan Jan, Boura Evzen
其它
Human
发表日期：2025
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Inhibitors of the 20S proteasome β5 subunit as potent and selective agents against Trichomonas vaginalis

20S蛋白酶体β5亚基抑制剂作为对抗阴道毛滴虫的有效且选择性药物

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00893-25
Miyamoto, Yukiko; Hurysz, Brianna M; Fajtova, Pavla; Eckmann, Peter; Serafim, Mateus Sá Magalhães; Kronenberger, Thales; Al-Hindy, Momen; Dekker, Patrick M; Maurits, Elmer; Overkleeft, Herman S; Bergdahl, B Mikael; Almaliti, Jehad; Gerwick, William H; O'Donoghue, Anthony J; Eckmann, Lars
发表日期：2025
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Recombinant proteasome provides new avenues for anti-malarial drug development.

重组蛋白酶体为抗疟药物的研发提供了新的途径

期刊:
影响因子:
doi:10.1101/2025.08.13.670186
Fajtova Pavla, Zhang Hanxiao, Urich Liam, da Silva Elany Barbosa, da Silva Cesar Hoffmann, Almaliti Jehad, Al-Hindy Momen, Boura Evzen, Fidock David A, Kirkman Laura A, Lin Gang, Bogyo Matthew, Gerwick William H, Zhao Jianhua, O'Donoghue Anthony J
其它
药物研究
发表日期：2025
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Structural insights into Salinosporamide A mediated inhibition of the human 20S proteasome.

盐霉素A介导的人类20S蛋白酶体抑制的结构见解

期刊:
影响因子:
doi:10.1101/2025.01.28.635221
Sülzen Hagen, Fajtova Pavla, O'Donoghue Anthony J, Boura Evzen, Silhan Jan
其它
Human
发表日期：2025
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Distinct substrate specificities of the three catalytic subunits of the Trichomonas vaginalis proteasome.

阴道毛滴虫蛋白酶体的三个催化亚基具有不同的底物特异性

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.5225
Fajtova Pavla, Hurysz Brianna M, Miyamoto Yukiko, Serafim Mateus Sá M, Jiang Zhenze, Vazquez Julia M, Trujillo Diego F, Liu Lawrence J, Somani Urvashi, Almaliti Jehad, Myers Samuel A, Caffrey Conor R, Gerwick William H, McMinn Dustin L, Kirk Christopher J, Boura Evzen, Eckmann Lars, O'Donoghue Anthony J
其它
发表日期：2024
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Development of subunit selective substrates for Trichomonas vaginalis proteasome

开发针对阴道毛滴虫蛋白酶体的亚基选择性底物

期刊:
影响因子:
doi:10.1101/2023.04.05.535794
Fajtova, Pavla; Hurysz, Brianna M; Miyamoto, Yukiko; Serafim, Mateus; Jiang, Zhenze; Trujillo, Diego F; Liu, Lawrence; Somani, Urvashi; Almaliti, Jehad; Myers, Samuel A; Caffrey, Conor R; Gerwick, William H; Kirk, Christopher J; Boura, Evzen; Eckmann, Lars; O'Donoghue, Anthony J
发表日期：2023
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A Charge-Switchable Zwitterionic Peptide for Rapid Detection of SARS-CoV-2 Main Protease

一种用于快速检测SARS-CoV-2主蛋白酶的电荷可切换两性离子肽

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202112995
Jin, Zhicheng; Mantri, Yash; Retout, Maurice; Cheng, Yong; Zhou, Jiajing; Jorns, Alec; Fajtova, Pavla; Yim, Wonjun; Moore, Colman; Xu, Ming; Creyer, Matthew N; Borum, Raina M; Zhou, Jingcheng; Wu, Zhuohong; He, Tengyu; Penny, William F; O'Donoghue, Anthony J; Jokerst, Jesse V
SARS-CoV-2
发表日期：2022
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