日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mycoestrogen Exposure during Pregnancy: Impact of the ABCG2 Q141K Variant on Birth and Placental Outcomes

妊娠期真菌雌激素暴露：ABCG2 Q141K 变异对分娩和胎盘结局的影响

期刊:Environmental Health Perspectives
影响因子:9.8
doi:10.1289/EHP14478
Rivera-Núñez, Zorimar; Kinkade, Carolyn; Brinker, Anita; Zhang, Ranran; Buckley, Brian; Brunner, Jessica; Ohman-Strickland, Pamela; Qiu, Xing; Qasem, Rani J; Fallon, John K; Smith, Philip C; Miller, Richard K; Salafia, Carolyn S; O'Connor, Thomas G; Aleksunes, Lauren M; Barrett, Emily S
微生物学
ABCG2
免疫/内分泌
发表日期：2025
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Evaluation of a human 3D multicellular hepatic spheroid model as a platform for studying hepatic transporters

评估人类三维多细胞肝球体模型作为研究肝脏转运蛋白的平台

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-05996-z
Hartauer, Mattie; Ho, Henry; Wan, Meimei; Murphy, William A; Tiley, Jacqueline B; Fallon, John K; Bishop, Colin E; Brouwer, Kim L R
细胞生物学
发表日期：2025
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Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity

雌激素与人类妊娠相关的细胞色素P450 3A活性增加

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1702419
Fashe, Muluneh M; Lee, Jonghwa; Grieco, Joseph T; Fallon, John K; Mulrenin, Ian R; Gower, Megan N; Jackson, Klarissa D; Boggess, Kim A; Lee, Craig R
细胞生物学
免疫/内分泌
发表日期：2025
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Development of an in vitro metabolic dysfunction-associated steatohepatitis model to investigate altered drug metabolizing enzymes, transport proteins, and hepatobiliary disposition

建立体外代谢功能障碍相关脂肪性肝炎模型，以研究药物代谢酶、转运蛋白和肝胆处置的改变

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1664808
Murphy, William A; Kyburz, Sarina; Ho, Henry; Loop, Matthew Shane; Fallon, John K; Tiley, Jacqueline B; Kralj, Thomas; Brouwer, Kim L R
肝炎
代谢
发表日期：2025
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N-acetyltransferase (NAT) 1 and NAT2 enzyme activities drive interindividual variability in sulfamethoxazole N-acetylation

N-乙酰转移酶 (NAT) 1 和 NAT2 的酶活性驱动磺胺甲噁唑 N-乙酰化的个体间差异。

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1016/j.dmd.2025.100195
Lanphier, Raeanne M; Latham, Bethany D; Gerringer, Amanda J; Interrante, Tyler; Jones, Corbin D; De Buysscher, Tristan; Fallon, John K; Jackson, Klarissa D
乙酰化
表观遗传
发表日期：2025
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Impact of variation in CYP3A and CYP2C8 on tucatinib metabolic clearance in human liver microsomes

CYP3A和CYP2C8变异对人肝微粒体中图卡替尼代谢清除率的影响

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1016/j.dmd.2025.100061
Latham, Bethany D; Montazeri, Pegah; Lobo, Licza F; Fallon, John K; Jackson, Klarissa D
代谢
发表日期：2025
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Interindividual variability in imatinib metabolism in human liver microsomes and primary human hepatocytes: Impact of CYP2C8 and CYP3A phenotypes

人肝微粒体和原代人肝细胞中伊马替尼代谢的个体间差异：CYP2C8 和 CYP3A 表型的影响

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1016/j.dmd.2025.100196
Latham, Bethany D; Montazeri, Pegah; Lanphier, Raeanne M; Gerringer, Amanda J; Interrante, Tyler; Jones, Corbin D; De Busysscher, Tristan; Fallon, John K; Jackson, Klarissa D
细胞生物学
代谢
发表日期：2025
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Impact of sex and pregnancy on hepatic CYP3A4 expression and activity in a humanized mouse model

性别和妊娠对人源化小鼠模型中肝脏CYP3A4表达和活性的影响

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1016/j.dmd.2024.100025
Fashe, Muluneh M; Miner, Taryn A; Collazo, Valeria Laboy; Grieco, Joseph T; Fallon, John K; Jackson, Klarissa D; Lee, Craig R
CYP3A4
发表日期：2025
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Impact of Pregnancy on the Pharmacokinetics and Metabolism of Nicotinamide in Humans

妊娠对人体烟酰胺药代动力学和代谢的影响

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.3146
Fashe, Muluneh M; Le, Tien V; Gower, Megan N; Mulrenin, Ian R; Dorman, Karen F; Smith, Spenser; Fallon, John K; Dumond, Julie B; Boggess, Kim A; Lee, Craig R
Human
发表日期：2024
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Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: a comparison to CYP3A substrates nifedipine and midazolam

妊娠相关激素可增加人肝细胞中CYP3A介导的丁丙诺啡代谢：与CYP3A底物硝苯地平和咪达唑仑的比较

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2023.1218703
Fashe, Muluneh M; Miner, Taryn A; Fallon, John K; Schauer, Amanda P; Sykes, Craig; Smith, Philip C; Lee, Craig R
代谢
细胞生物学
免疫/内分泌
发表日期：2023
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