Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation.

在脊神经结扎大鼠模型中，抑制 S100A4 可降低神经毒性星形胶质细胞的反应性，并通过 TLR4/NF-κB 通路减轻神经性疼痛