日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cotargeting DNA topoisomerase II enhances efficacy of RAS-targeted therapy in KRAS-mutant cancer models

在KRAS突变癌症模型中，联合靶向DNA拓扑异构酶II可增强RAS靶向治疗的疗效。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI197192
Xu, Rongzhong; Wang, Dongsheng; Ma, Guangzhi; Yuan, Xun; Chu, Qian; Fan, Songqing; Zhang, Rener; Du, Pan; Jia, Shidong; Leal, Ticiana A; Ramalingam, Suresh S; Chen, Zhen; Sun, Shi-Yong
RAS
肿瘤
肿瘤免疫
发表日期：2026
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The Role of Hedgehog Signaling in Non-small Cell Lung Cancer: Targeting Tumor Invasion, Therapy Resistance and Novel Therapeutic Strategies

Hedgehog信号通路在非小细胞肺癌中的作用：靶向肿瘤侵袭、治疗耐药性和新型治疗策略

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.123287
Kang, Yu; Zheng, Hongmei; Wen, Qiuyuan; Fan, Songqing
肺癌
肿瘤
肿瘤免疫
信号转导
治疗耐药
Hedgehog
细胞生物学
发表日期：2026
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Itraconazole Reversing Acquired Resistance to Osimertinib in NSCLC by Inhibiting the SHH/DUSP13B/p-STAT3 Axis

伊曲康唑通过抑制SHH/DUSP13B/p-STAT3轴逆转非小细胞肺癌对奥希替尼的获得性耐药

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202409416
Zheng, Hongmei; Tang, Yaoxiang; Zang, Hongjing; Luo, Jiadi; Zhou, Hanqiong; Zhan, Yuting; Zou, Ying; Wen, Qiuyuan; Ma, Jian; Fan, Songqing
肺癌
肿瘤
肿瘤免疫
SHH
JAK/STAT
STAT3
SP1
细胞生物学
发表日期：2025
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TRIM25 degrades BRD7 protein stability through the ubiquitin proteasome pathway to promote breast cancer progression and paclitaxel resistance by activating YB1/Bcl-2 transcription axis.

TRIM25 通过泛素蛋白酶体途径降低 BRD7 蛋白的稳定性，通过激活 YB1/Bcl-2 转录轴促进乳腺癌进展和紫杉醇耐药性。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-08140-8
Xue Changning, Wei Qingqing, Li Mengna, Wei Jianxia, Zheng Lemei, Wu Zubing, Xin Huizhen, Duan Yumei, Fan Songqing, Xiong Wei, Li Guiyuan, Tang Faqing, Deng Hongyu, Zhou Ming
Bcl-2
肿瘤
肿瘤免疫
BRD7
乳腺癌
YB1
发表日期：2025
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A novel biguanide-derivative promotes NEDD4-mediated FGFR1 ubiquitination through BMI1 to overcome osimertinib resistance in NSCLC

一种新型双胍衍生物通过BMI1促进NEDD4介导的FGFR1泛素化，从而克服非小细胞肺癌中的奥希替尼耐药性。

期刊:Cancer Biology & Medicine
影响因子:8.4
doi:10.20892/j.issn.2095-3941.2025.0209
Peng, Mei; Wang, Weifan; Xiao, Di; Li, Duo; Deng, Jun; Zou, Hui; Feng, Xing; Yang, Yunhai; Fan, Songqing; Yang, Xiaoping
肺癌
肿瘤
表观遗传
肿瘤免疫
泛素化
细胞生物学
NEDD4
FGFR1
发表日期：2025
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Unveiling immune resistance mechanisms in nasopharyngeal carcinoma and emerging targets for antitumor immune response: tertiary lymphoid structures

揭示鼻咽癌的免疫抵抗机制及抗肿瘤免疫反应的新兴靶点：三级淋巴结构

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-024-05880-7
Wang, Huilin; Zhan, Yuting; Luo, Jiadi; Wang, Weiyuan; Fan, Songqing
鼻咽癌
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2025
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YWHAG promotes the progression of lung adenocarcinoma through the JAK2/STAT3 pathway.

YWHAG 通过 JAK2/STAT3 通路促进肺腺癌的进展

期刊:Cancer Cell International
影响因子:6
doi:10.1186/s12935-025-03730-0
Zheng Hongmei, Tang Yaoxiang, Zang Hongjing, Luo Jiadi, Zhou Hanqiong, Zou Ying, Peng Jinwu, Fan Songqing
肿瘤
肺癌
肿瘤免疫
发表日期：2025
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A pan-cancer analysis of MARCH8: molecular characteristics, clinical relevance, and immuno-oncology features.

MARCH8 的泛癌分析：分子特征、临床相关性和免疫肿瘤学特征

期刊:Cancer Biology & Therapy
影响因子:4.6
doi:10.1080/15384047.2025.2458773
Quan Zihan, Fan Songqing, Zheng Hongmei, Ning Yue, Yang Yang
肿瘤
肿瘤免疫
发表日期：2025
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NSUN2 Negatively Regulates TP53 mRNA Stability to Promote the Malignant Progression of Nasopharyngeal Carcinoma

NSUN2负调控TP53 mRNA稳定性以促进鼻咽癌的恶性进展

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17243950
Zheng, Lemei; Wei, Jianxia; Li, Xiaolong; Li, Mengna; Xue, Changning; Chen, Shipeng; Wei, Qingqing; Fan, Songqing; Xiong, Wei; Zhou, Ming; Deng, Hongyu
肿瘤
肿瘤免疫
信号转导
P53
鼻咽癌
发表日期：2025
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MicroRNA-150-3p enhances the antitumour effects of CGP57380 and is associated with a favourable prognosis in non-small cell lung cancer

MicroRNA-150-3p增强CGP57380的抗肿瘤作用，并与非小细胞肺癌的良好预后相关。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-85793-7
Zheng, Hongmei; Fan, Songqing; Luo, Jiadi; Wen, Qiuyuan; Zang, Hongjing
肺癌
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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