Fan-Fan相关文献与解析，生知库 | 链接生命科学的每一步

Fan, Fan; Xi, Bin; Meng, Xianghu; Wang, Han; Zhang, Bowen; Xu, Qingbo; Feng, Wei; Gao, Wenfeng; Wang, Xiaoman; Wang, Yuji; Zhang, Hongbo; Zhou, Feng; Liu, Zhenming; Zhou, Wenbiao; Huang, Bo

3D/类器官

发表日期：2026

文献求助收藏

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury.

单细胞和空间转录组学揭示肾损伤后促炎和促纤维化微环境。

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202503691

Li Li, Liao Jinlin, Zhang Yuxi, Yao Zifu, Huang Junxin, Wu Kejia, Li Lu, Peng Yiling, Zhu Haili, Hong Xue, Liu Xi, Zhou Lili, Hou Fan Fan, Fu Haiyan, Liu Youhua

cRGD-Functionalized macrophage extracellular vesicles loaded with GSK2033 enhance T cell antitumor immunity in GBM by disrupting the LXR/ABCA1-Mediated Myelin lipid transfer axis.

载有 GSK2033 的 cRGD 功能化巨噬细胞细胞外囊泡通过破坏 LXR/ABCA1 介导的髓鞘脂质转移轴增强 GBM 中的 T 细胞抗肿瘤免疫力。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-026-04116-8

Bi Changlong, Lan Song, Sun Zhongyi, Fan Fan, Luo Xiangying

The EAT-Lancet planetary health diet and risk of incident chronic kidney disease

EAT-Lancet 行星健康饮食与慢性肾脏病发病风险

期刊:Canadian Medical Association Journal

影响因子:11.3

doi:10.1503/cmaj.250457

Yang, Sisi; Huang, Yu; Ye, Ziliang; Gan, Xiaoqin; Zhang, Yanjun; Xiang, Hao; Wu, Yiting; Zhang, Yiwei; Zhang, Yuanyuan; Nie, Sheng; Hou, Fan Fan; Qin, Xianhui

发表日期：2026

文献求助收藏

In vivo CAR-cell therapy: current challenges and emerging therapeutic advances

体内CAR细胞疗法：当前挑战与新兴治疗进展

期刊:Molecular Biomedicine

影响因子:10.1

doi:10.1186/s43556-026-00447-y

Yang, Yi-Min; Bao, Bo; Cao, Yu-Hao; Yao, Jin; Ding, Yu-Fan; Hu, Yi-Yang; Fan, Fan; Zhao, Jun-Long

细胞生物学

发表日期：2026

文献求助收藏

Bionic Nanoparticle Hydrogel for Astrocyte-Targeted Estradiol Delivery Ameliorates Perimenopausal Depression via P2X7 Receptor Inhibition.

仿生纳米颗粒水凝胶靶向星形胶质细胞递送雌二醇，通过抑制 P2X7 受体改善围绝经期抑郁症。

期刊:Biomaterials Research

影响因子:9.6

doi:10.34133/bmr.0336

Chu Ketan, Chen Peiqiong, Xu Wenxian, Zhu Chengya, Xu Li, Li Chunming, Wu Fan, Fan Huiyu, Zheng Xiaoling, Zhou Jianhong

Sino-C, a novel sinomenine derivative, induces cell death by disrupting cholesterol homeostasis in colorectal cancer cells.

Sino-C 是一种新型的青藤碱衍生物，它通过破坏结直肠癌细胞中的胆固醇稳态来诱导细胞死亡。

期刊:Acta Pharmacologica Sinica

影响因子:8.4

doi:10.1038/s41401-025-01683-8

Zhang Yan-Ming, Lu Hui, Xiao Bing-Jie, Xu Chun-Cao, Zhou Fan-Fan, Li Ting, Zhan Zha-Jun, Lu Jin-Jian

FFAR4 negatively regulates colorectal cancer growth via blocking oxidative phosphorylation

FFAR4通过阻断氧化磷酸化负调控结直肠癌的生长

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-026-07942-4

Wei, Lengyun; Wei, Wei; Wang, Qun; Li, Dashuai; Hu, Benfei; Fan, Fan; Liu, Chenfeng; Long, Pengpeng

Kidney Tertiary Lymphoid Tissues and Poor Immunosuppressive Response in IgA Nephropathy.

IgA肾病中肾脏三级淋巴组织和免疫抑制反应不良。

期刊:Kidney International Reports

影响因子:5.7

doi:10.1016/j.ekir.2025.11.003

Zhao Hao, Ma Rui, Zhong Zhuoni, Xie Di, Ouyang Han, Zhou Zhanmei, Su Cailing, Jia Nan, Xu Xin, Hou Fan Fan

A large-scale concordance study of toxicity findings across preclinical species and humans for small molecules and biologics

一项针对小分子药物和生物制剂在临床前动物和人体中的毒性结果的大规模一致性研究

期刊:Frontiers in Toxicology

影响因子:4.6

doi:10.3389/ftox.2026.1731947

Assessing conformation validity and rationality of deep learning-generated 3D molecules

评估深度学习生成的3D分子的构象有效性和合理性

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury.

单细胞和空间转录组学揭示肾损伤后促炎和促纤维化微环境。

cRGD-Functionalized macrophage extracellular vesicles loaded with GSK2033 enhance T cell antitumor immunity in GBM by disrupting the LXR/ABCA1-Mediated Myelin lipid transfer axis.

载有 GSK2033 的 cRGD 功能化巨噬细胞细胞外囊泡通过破坏 LXR/ABCA1 介导的髓鞘脂质转移轴增强 GBM 中的 T 细胞抗肿瘤免疫力。

The EAT-Lancet planetary health diet and risk of incident chronic kidney disease

EAT-Lancet 行星健康饮食与慢性肾脏病发病风险

In vivo CAR-cell therapy: current challenges and emerging therapeutic advances

体内CAR细胞疗法：当前挑战与新兴治疗进展

Bionic Nanoparticle Hydrogel for Astrocyte-Targeted Estradiol Delivery Ameliorates Perimenopausal Depression via P2X7 Receptor Inhibition.

仿生纳米颗粒水凝胶靶向星形胶质细胞递送雌二醇，通过抑制 P2X7 受体改善围绝经期抑郁症。

Sino-C, a novel sinomenine derivative, induces cell death by disrupting cholesterol homeostasis in colorectal cancer cells.

Sino-C 是一种新型的青藤碱衍生物，它通过破坏结直肠癌细胞中的胆固醇稳态来诱导细胞死亡。

FFAR4 negatively regulates colorectal cancer growth via blocking oxidative phosphorylation

FFAR4通过阻断氧化磷酸化负调控结直肠癌的生长

Kidney Tertiary Lymphoid Tissues and Poor Immunosuppressive Response in IgA Nephropathy.

IgA肾病中肾脏三级淋巴组织和免疫抑制反应不良。

A large-scale concordance study of toxicity findings across preclinical species and humans for small molecules and biologics

一项针对小分子药物和生物制剂在临床前动物和人体中的毒性结果的大规模一致性研究