FanYing Meng相关文献与解析，生知库 | 链接生命科学的每一步

Hypoxia-Targeting Drug Evofosfamide (TH-302) Enhances Sunitinib Activity in Neuroblastoma Xenograft Models

缺氧靶向药物 Evofosfamide (TH-302) 可增强神经母细胞瘤异种移植模型中的舒尼替尼活性

doi:10.1016/j.tranon.2018.05.004

Sushil Kumar, Jessica D Sun, Libo Zhang, Reza Bayat Mokhtari, Bing Wu, Fanying Meng, Qian Liu, Deepthi Bhupathi, Yan Wang, Herman Yeger, Charles Hart, Sylvain Baruchel

SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids

人类胎儿肝细胞中的 SIRT1 破坏导致葡萄糖和脂质积累增加

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0149344

Takamasa Tobita, Jorge Guzman-Lepe, Kazuki Takeishi, Toshimasa Nakao, Yang Wang, Fanying Meng, Chu-Xia Deng, Alexandra Collin de l'Hortet, Alejandro Soto-Gutierrez

Efficacy and safety of the hypoxia-activated prodrug TH-302 in combination with gemcitabine and nab-paclitaxel in human tumor xenograft models of pancreatic cancer

缺氧激活前药 TH-302 与吉西他滨和白蛋白结合型紫杉醇联合用于胰腺癌人肿瘤异种移植模型的疗效和安全性

期刊:Cancer Biology & Therapy

影响因子:4.4

doi:10.1080/15384047.2014.1003005

Jessica D Sun, Qian Liu, Dharmendra Ahluwalia, Wenwu Li, Fanying Meng, Yan Wang, Deepthi Bhupathi, Ayesha S Ruprell, Charles P Hart

Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition

Chk1 抑制增强缺氧激活前药 TH-302 的抗肿瘤活性

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-015-1387-6

Fanying Meng, Deepthi Bhupathi, Jessica D Sun, Qian Liu, Dharmendra Ahluwalia, Yan Wang, Mark D Matteucci, Charles P Hart

肿瘤

发表日期：2015

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Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302

缺氧激活前药 TH-302 的分子和细胞药理学

期刊:Molecular Cancer Therapeutics

影响因子:5.3

doi:10.1158/1535-7163.MCT-11-0634

Fanying Meng, James W Evans, Deepthi Bhupathi, Monica Banica, Leslie Lan, Gustavo Lorente, Jian-Xin Duan, Xiaohong Cai, Alexandra M Mowday, Christopher P Guise, Andrej Maroz, Robert F Anderson, Adam V Patterson, Gregory C Stachelek, Peter M Glazer, Mark D Matteucci, Charles P Hart

Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function

CC 趋化因子配体 2 功能的新型杂芳酰苯脲拮抗剂的发现、优化和药理学表征

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/jm1012903

Edgardo Laborde, Robert W Macsata, Fanying Meng, Brian T Peterson, Louise Robinson, Steve R Schow, Reyna J Simon, Hua Xu, Kunihisa Baba, Hideaki Inagaki, Yoshiro Ishiwata, Takahito Jomori, Yukiharu Matsumoto, Atsushi Miyachi, Takashi Nakamura, Masayuki Okamoto, Tracy M Handel, Claude C A Bernard

信号转导

发表日期：2011

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Protective effect and mechanism of Polygonatum kingianum against hypoxia-induced injury

黄精对缺氧损伤的保护作用及机制

Hypoxia-Targeting Drug Evofosfamide (TH-302) Enhances Sunitinib Activity in Neuroblastoma Xenograft Models

缺氧靶向药物 Evofosfamide (TH-302) 可增强神经母细胞瘤异种移植模型中的舒尼替尼活性

SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids

人类胎儿肝细胞中的 SIRT1 破坏导致葡萄糖和脂质积累增加

Efficacy and safety of the hypoxia-activated prodrug TH-302 in combination with gemcitabine and nab-paclitaxel in human tumor xenograft models of pancreatic cancer

缺氧激活前药 TH-302 与吉西他滨和白蛋白结合型紫杉醇联合用于胰腺癌人肿瘤异种移植模型的疗效和安全性

Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition

Chk1 抑制增强缺氧激活前药 TH-302 的抗肿瘤活性

Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302

缺氧激活前药 TH-302 的分子和细胞药理学

Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function

CC 趋化因子配体 2 功能的新型杂芳酰苯脲拮抗剂的发现、优化和药理学表征