日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Network Medicine-Based Strategy Identifies Maprotiline as a Repurposable Drug by Inhibiting PD-L1 Expression via Targeting SPOP in Cancer

基于网络医学的策略发现，马普替林可通过靶向SPOP抑制PD-L1表达，从而成为一种可重新利用的药物。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202410285
Tian, Saisai; Xu, Mengting; Geng, Xiangxin; Fang, Jiansong; Xu, Hanchen; Xue, Xinying; Hu, Hongmei; Zhang, Qing; Yu, Dianping; Guo, Mengmeng; Zhang, Hongwei; Lu, Jinyuan; Guo, Chengyang; Wang, Qun; Liu, Sanhong; Zhang, Weidong
PD-L1
SPOP
发表日期：2025
文献求助 收藏

Exploring the Therapeutic Mechanism of Xinbao Pill in Brain Injury After Cardiopulmonary Resuscitation Based on Network Pharmacology, Metabolomics, and Experimental Verification

基于网络药理学、代谢组学和实验验证，探讨心肺复苏后脑损伤中欣宝丸的治疗机制

期刊:CNS Neuroscience & Therapeutics
影响因子:5
doi:10.1111/cns.70297
Li, Dongli; Wu, Qihui; Li, Zunjiang; Chen, Baijian; Sun, Xing; Wu, Qiqi; Ding, Zhenzhu; Liu, Linling; Fang, Jiansong; Zeng, Ruifeng; Gu, Yong; Ding, Banghan
神经科学
代谢
发表日期：2025
文献求助 收藏

SZBC-AI4TCM: a comprehensive web-based computing platform for traditional Chinese medicine research and development

SZBC-AI4TCM：一个面向传统中医药研发的综合性网络计算平台

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1698202
Lang, Jidong; Guo, Kaimin; Yang, Jinna; Yang, Pengcheng; Wei, Yu; Han, Jingwen; Zhao, Shuang; Liu, Zhihong; Yi, Haowei; Yan, Xin; Chen, Binbin; Wang, Cheng; Xu, Jian; Ge, Jiawei; Zhang, Wen; Zhou, Xuezhong; Fang, Jiansong; Su, Jing; Yan, Kaijing; Hu, Yunhui; Wang, Wenjia
发表日期：2025
文献求助 收藏

Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.

人参皂苷 Ro 通过 IBA1/GFAP-MAPK 信号通路改善 APP/PS1 小鼠的认知障碍和神经炎症

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1528590
Li Tianyao, Chen Jiaxin, Xie Zhouyuan, Fang Jiansong, Wu Qiqing, Cao Xinyue, Chen Ziying, Wang Yiyun, Fan Qiqi, Wang Qi, Liu Jinman
神经科学
GFAP
炎症
发表日期：2025
文献求助 收藏

3-Hydroxybutyrate, a metabolite in sustaining neuronal cell vitality: a mendelian randomization and in vitro experimentation.

3-羟基丁酸，一种维持神经元细胞活力的代谢物：孟德尔随机化和体外实验

期刊:Nutrition & Metabolism
影响因子:4.1
doi:10.1186/s12986-025-00960-x
Hu Xiaoling, Lin Yu, Huang Kaiwen, Xu HuiLin, Fu Changmei Huang, Ou Jiayin, Fan Xiude, Li Zhe, Fang Jiansong, Fang Shuhuan
代谢
发表日期：2025
文献求助 收藏

Pharmacovigilance analysis of vision disorders relating to brimonidine treatment and mechanism study using network toxicology and molecular docking

利用网络毒理学和分子对接技术对溴莫尼定治疗相关的视力障碍进行药物警戒分析和机制研究

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-29593-z
Xu, Lvjie; Zhao, Shuyang; Zhao, Sixuan; Wang, Zhe; Fang, Jiansong; Cai, Chuipu; Wang, Jiawei
发表日期：2025
文献求助 收藏

Protein-centric omics analysis reveals circulating complements linked to non-viral liver diseases as potential therapeutic targets

以蛋白质为中心的组学分析揭示了与非病毒性肝病相关的循环补体作为潜在的治疗靶点。

期刊:Clinical and Molecular Hepatology
影响因子:16.9
doi:10.3350/cmh.2023.0343
Shi, Yingzhou; Dong, Hang; Sun, Shiwei; Wu, Xiaoqin; Fang, Jiansong; Zhao, Jianbo; Han, Junming; Li, Zongyue; Wu, Huixiao; Liu, Luna; Wu, Wanhong; Tian, Yang; Yuan, Guandou; Fan, Xiude; Xu, Chao
毒理研究
微生物学
免疫/内分泌
发表日期：2024
文献求助 收藏

Inhalable Bottlebrush Polymer Bioconjugates as Vectors for Efficient Pulmonary Delivery of Oligonucleotides

可吸入瓶刷聚合物生物共轭物作为高效肺部输送寡核苷酸的载体

期刊:ACS Nano
影响因子:15.8
doi:10.1021/acsnano.3c08660
Yang Fang, Jiansong Cai, Mengqi Ren, Tongtong Zhong, Dali Wang, Ke Zhang
信号转导
发表日期：2024
文献求助 收藏

Network Medicine: A Potential Approach for Virtual Drug Screening

网络医学：一种潜在的虚拟药物筛选方法

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph17070899
Ma, Mingxuan; Huang, Mei; He, Yinting; Fang, Jiansong; Li, Jiachao; Li, Xiaohan; Liu, Mengchen; Zhou, Mei; Cui, Guozhen; Fan, Qing
发表日期：2024
文献求助 收藏

Network-based identification and mechanism exploration of active ingredients against Alzheimer's disease via targeting endoplasmic reticulum stress from traditional chinese medicine

基于网络的中药活性成分靶向内质网应激治疗阿尔茨海默病机制研究

期刊:Computational and Structural Biotechnology Journal
影响因子:4.1
doi:10.1016/j.csbj.2023.12.017
Dai, Zhao; Hu, Tian; Wei, Junwen; Wang, Xue; Cai, Chuipu; Gu, Yong; Hu, Yunhui; Wang, Wenjia; Wu, Qihui; Fang, Jiansong
内质网应激
阿尔茨海默症
发表日期：2024
文献求助 收藏