Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
哌拉汀通过减弱MAPKs/NF-κB信号通路和NLRP3炎症小体激活发挥对LPS诱导的脓毒症的保护作用
期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph14060588
Huang, Chi-Han; Wang, Shu-Chi; Chen, I-Chen; Chen, Yi-Ting; Liu, Po-Len; Fang, Shih-Hua; Huang, Shu-Pin; Yeh, Hsin-Chih; Liu, Ching-Chih; Lee, Po-Yen; Lin, Tzu-Chieh; Cheng, Wei-Chung; Su, Chia-Cheng; Wu, Hsin-En; Chen, Yuan-Ru; Li, Chia-Yang
炎症
炎症/感染
信号转导
NF-κB
败血症
MAPK/ERK
LRP3
NLRP3
炎性小体
免疫/内分泌
