Oxycodone is associated with dose-dependent QTc prolongation in patients and low-affinity inhibiting of hERG activity in vitro
羟考酮与患者剂量依赖性的QTc间期延长有关,并且在体外对hERG活性具有低亲和力抑制作用。
期刊:British Journal of Clinical Pharmacology
影响因子:3
doi:10.1111/j.1365-2125.2008.03327.x
Fanoe, Søren; Jensen, Gorm Boje; Sjøgren, Per; Korsgaard, Mads P G; Grunnet, Morten