日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pre-incubation with OATP1B1 and OATP1B3 inhibitors potentiates inhibitory effects in physiologically relevant sandwich-cultured primary human hepatocytes

用 OATP1B1 和 OATP1B3 抑制剂进行预孵育可增强其在生理相关的夹层培养的原代人肝细胞中的抑制作用。

Farasyn, Taleah; Pahwa, Sonia; Xu, Chao; Yue, Wei

Development of a Rat Sandwich-Cultured Hepatocytes Model Expressing Functional Human Organic Anion Transporting Polypeptide (OATP) 1B3: A Potential Screening Tool for Liver-Targeting Compounds

构建表达功能性人有机阴离子转运多肽(OATP)1B3的大鼠三明治培养肝细胞模型:一种潜在的肝脏靶向化合物筛选工具

Farasyn, Taleah; Xu, Chao; Yue, Wei

Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interaction Potential of Vemurafenib Using R-Value and Physiologically-Based Pharmacokinetic Models

利用R值和基于生理的药代动力学模型评估维莫非尼的OATP1B1和OATP1B3介导的药物相互作用潜力

Kayesh, Ruhul; Farasyn, Taleah; Crowe, Alexandra; Liu, Qiang; Pahwa, Sonia; Alam, Khondoker; Neuhoff, Sibylle; Hatley, Oliver; Ding, Kai; Yue, Wei

Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions.

用依维莫司和西罗莫司进行预孵育可降低有机阴离子转运多肽 (OATP)1B1 和 1B3 介导的转运,且与 mTOR 激酶抑制无关:对评估 OATP1B1 和 OATP1B3 介导的药物相互作用的意义

Farasyn Taleah, Crowe Alexandra, Hatley Oliver, Neuhoff Sibylle, Alam Khondoker, Kanyo Jean, Lam TuKiet T, Ding Kai, Yue Wei

Characterization of Liver- and Cancer-type-Organic Anion Transporting Polypeptide (OATP) 1B3 Messenger RNA Expression in Normal and Cancerous Human Tissues

肝癌型有机阴离子转运多肽(OATP)1B3信使RNA在正常和癌变人体组织中的表达特征

Alam, Khondoker; Farasyn, Taleah; Ding, Kai; Yue, Wei

Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner.

用蛋白酶体抑制剂硼替佐米治疗可降低有机阴离子转运多肽 (OATP) 1B3 介导的转运,且这种降低是底物依赖性的

Alam Khondoker, Farasyn Taleah, Crowe Alexandra, Ding Kai, Yue Wei

Generation and characterization of a JAK2V617F-containing erythroleukemia cell line

构建和鉴定含JAK2V617F突变的红白血病细胞系

Zhao, Wanke; Zou, Kang; Farasyn, Taleah; Ho, Wanting Tina; Zhao, Zhizhuang Joe