Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells
线粒体复合物 I 抑制会引发线粒体自噬依赖性 ROS 增加，从而导致黑色素瘤细胞坏死性凋亡和铁凋亡
期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/cddis.2017.133
Farhan Basit, Lisanne Mpe van Oppen, Laura Schöckel, Hasse M Bossenbroek, Sjenet E van Emst-de Vries, Johannes Cw Hermeling, Sander Grefte, Charlotte Kopitz, Melanie Heroult, Peter Hgm Willems, Werner Jh Koopman
信号转导
细胞生物学
肿瘤
黑色素瘤
肿瘤细胞
Apoptosis
Autophagy
