日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene conversion is a key driver of diversity hotspots in M. tuberculosis antigens and virulence-associated loci

基因转换是结核分枝杆菌抗原和毒力相关基因位点多样性热点的关键驱动因素。

Marin, Maximillian G; Quinones-Olvera, Natalia; Jin, Hu; Harris, Michael A; Jeffrey, Brendan M; Rosenthal, Alex; Murphy, Kenan C; Sassetti, Christopher; Li, Heng; Farhat, Maha R

Benchmarking within-sample minority variant detection with short-read sequencing in M. tuberculosis

利用短读测序技术对结核分枝杆菌样本内少数变异体检测进行基准测试

Mulaudzi, Shandukani; Kulkarni, Sanjana; Marin, Maximillian G; Farhat, Maha R

Multivariable regression models improve accuracy and sensitive grading of antibiotic resistance mutations in Mycobacterium tuberculosis

多变量回归模型提高了结核分枝杆菌抗生素耐药突变的准确性和敏感性分级

Kulkarni, Sanjana G; Laurent, Sacha; Miotto, Paolo; Walker, Timothy M; Chindelevitch, Leonid; Nathanson, Carl-Michael; Ismail, Nazir; Rodwell, Timothy C; Farhat, Maha R

Precision phenotyping for curating research cohorts of patients with unexplained post-acute sequelae of COVID-19

精准表型分析用于构建新冠肺炎不明原因后遗症患者研究队列

Azhir, Alaleh; Hügel, Jonas; Tian, Jiazi; Cheng, Jingya; Bassett, Ingrid V; Bell, Douglas S; Bernstam, Elmer V; Farhat, Maha R; Henderson, Darren W; Lau, Emily S; Morris, Michele; Semenov, Yevgeniy R; Triant, Virginia A; Visweswaran, Shyam; Strasser, Zachary H; Klann, Jeffrey G; Murphy, Shawn N; Estiri, Hossein

Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures.

频繁出现的 ESX-1 相关相变异体影响结核分枝杆菌在宿主和抗生素压力下的适应性

Luna Michael J, Oluoch Peter O, Miao Jiazheng, Culviner Peter, Papavinasasundaram Kadamba, Jaecklein Eleni, Shell Scarlet S, Ioerger Thomas R, Fortune Sarah M, Farhat Maha R, Sassetti Christopher M

Complete genome sequence of a virulent barcoded Mycobacterium tuberculosis str. Erdman commonly used for non-human primate infection studies

用于非人灵长类动物感染研究的强毒力结核分枝杆菌Erdman菌株的完整基因组序列

Marin, Maximilian G; Chase, Michael R; Quinones, Natalia; Wakabayashi, Shoko; Mugahid, Douaa; Fortune, Sarah M; Farhat, Maha R; Chao, Michael C

Tuberculosis disease severity assessment using clinical variables and radiology enabled by artificial intelligence

利用人工智能结合临床变量和放射学数据进行结核病病情严重程度评估

Ghanem, Marwan; Srivastava, Ratnam; Ektefaie, Yasha; Hoppes, Drew; Rosenfeld, Gabriel; Yaniv, Ziv; Grinev, Alina; Xu, Ava Y; Yang, Eunsol; Velásquez, Gustavo E; Harrison, Linda; Rosenthal, Alex; Savic, Radojka M; Jacobson, Karen R; Farhat, Maha R

The structural context of mutations in proteins predicts their effect on antibiotic resistance

蛋白质突变的结构背景可以预测其对抗生素耐药性的影响。

Green, Anna G; Tasmin, Mahbuba; Vargas, Roger Jr; Farhat, Maha R

Pitfalls of bacterial pan-genome analysis approaches: a case study of Mycobacterium tuberculosis and two less clonal bacterial species

细菌泛基因组分析方法的缺陷:以结核分枝杆菌和两种克隆性较低的细菌为例

Marin, Maximillian G; Quinones-Olvera, Natalia; Wippel, Christoph; Behruznia, Mahboobeh; Jeffrey, Brendan M; Harris, Michael; Mann, Brendon C; Rosenthal, Alex; Jacobson, Karen R; Warren, Robin M; Li, Heng; Meehan, Conor J; Farhat, Maha R

Patient Determinants and Effects on Adherence of Adverse Drug Reactions to Tuberculosis Treatment: A Prospective Cohort Analysis

结核病治疗中药物不良反应的患者决定因素及其对治疗依从性的影响:一项前瞻性队列分析

Tzelios, Christine A; Malatesta, Samantha; Carney, Tara; White, Laura F; Weber, Sarah E; Thomson, Sarah; Theron, Danie; Myers, Bronwyn; Parry, Charles D H; Warren, Robin M; Horsburgh, C Robert; Farhat, Maha R; Jacobson, Karen R