日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanistic basis and therapeutic modulation of T cell fitness to enhance CAR-T cell efficacy in hematological malignancies

增强CAR-T细胞在血液系统恶性肿瘤治疗中疗效的机制基础及T细胞适应性治疗调控

Makni-Maalej, Karama; Alotaibi, Shaykhah Mujahhiz; Fernandes, Queenie; Ahmed, Syed Osman; Mestiri, Sarra; Bougarn, Salim; Amir, Waad; Farhatullah, Syed; Kharfan-Dabaja, Mohamed; Merhi, Maysaloun; Fakih, Riad El; Aljurf, Mahmoud; Dermime, Said

Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options

脐带血T细胞可通过CD62L选择进行分离和富集,用于“现成的”嵌合抗原受体T细胞疗法,从而拓宽移植选择。

Georgiadis, Christos; Nickolay, Lauren; Syed, Farhatullah; Zhan, Hong; Gkazi, Soragia Athina; Etuk, Annie; Abramowski-Mock, Ulrike; Preece, Roland; Cuber, Piotr; Adams, Stuart; Ottaviano, Giorgio; Qasim, Waseem

Integrin-Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor-Specific Delivery Achieve MYCN Silencing with Improved Survival

整合素靶向短干扰 RNA 纳米复合物用于神经母细胞瘤肿瘤特异性递送,实现 MYCN 沉默并提高生存率

Aristides D Tagalakis, Vignesh Jayarajan, Ruhina Maeshima, Kin H Ho, Farhatullah Syed, Lin-Ping Wu, Ahmad M Aldossary, Mustafa M Munye, Talisa Mistry, Olumide Kayode Ogunbiyi, Arturo Sala, Joseph F Standing, Seyed M Moghimi, Andrew W Stoker, Stephen L Hart

Determination of antimicrobial and phytochemical compounds of Jatropha curcas plant

麻风树植物抗菌和植物化学成分的测定

Rahu, Muhammad Idrees; Naqvi, Syed Habib Ahmed; Memon, Nazakat Hussain; Idrees, Muhammad; Kandhro, Farhatullah; Pathan, Navish Lodhi; Sarker, Md Nazirul Islam; Aqeel Bhutto, Muhammad

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

慢病毒成纤维细胞基因治疗隐性营养不良型大疱性表皮松解症的安全性和早期疗效结果

Su M Lwin, Farhatullah Syed, Wei-Li Di, Tendai Kadiyirire, Lu Liu, Alyson Guy, Anastasia Petrova, Alya Abdul-Wahab, Fiona Reid, Rachel Phillips, Maria Elstad, Christos Georgiadis, Sophia Aristodemou, Patricia A Lovell, James R McMillan, John Mee, Snaigune Miskinyte, Matthias Titeux, Linda Ozoemena, 

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB

慢病毒工程改造的成纤维细胞表达密码子优化的COL7A1,可恢复RDEB中的锚定原纤维。

Georgiadis, Christos; Syed, Farhatullah; Petrova, Anastasia; Abdul-Wahab, Alya; Lwin, Su M; Farzaneh, Farzin; Chan, Lucas; Ghani, Sumera; Fleck, Roland A; Glover, Leanne; McMillan, James R; Chen, Mei; Thrasher, Adrian J; McGrath, John A; Di, Wei-Li; Qasim, Waseem

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1

与 MKL1 功能丧失纯合突变相关的免疫缺陷和严重易感细菌感染

Julien Record, Dessislava Malinova, Helen L Zenner, Vincent Plagnol, Karolin Nowak, Farhatullah Syed, Gerben Bouma, James Curtis, Kimberly Gilmour, Catherine Cale, Scott Hackett, Guillaume Charras, Dale Moulding, Sergey Nejentsev, Adrian J Thrasher, Siobhan O Burns

Potential role of Notch signalling in CD34+ chronic myeloid leukaemia cells: cross-talk between Notch and BCR-ABL

Notch 信号在 CD34+ 慢性粒细胞白血病细胞中的潜在作用:Notch 与 BCR-ABL 之间的串扰

Abdullah Aljedai, Anne-Marie Buckle, Prashant Hiwarkar, Farhatullah Syed

Site-specific keloid fibroblasts alter the behaviour of normal skin and normal scar fibroblasts through paracrine signalling

部位特异性瘢痕疙瘩成纤维细胞通过旁分泌信号改变正常皮肤和正常瘢痕成纤维细胞的行为

Kevin J Ashcroft, Farhatullah Syed, Ardeshir Bayat

Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor

通过使用新型双重 TORC1/2 抑制剂拮抗过度的 mTOR 信号传导,可以抑制瘢痕疙瘩病

Farhatullah Syed, David Sherris, Ralf Paus, Shohreh Varmeh, Subir Singh, Pier P Pandolfi, Ardeshir Bayat