日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Disrupting the KRAS-SOS1 protein-protein interaction: mechanistic rationale for pan-KRAS pathway suppression and combination therapy

破坏KRAS-SOS1蛋白-蛋白相互作用:泛KRAS通路抑制和联合治疗的机制原理

Kamel, Emadeldin M; Khadrawy, Sally Mostafa; Ali, Mohamed A M; Abukhadra, Mostafa R; Yassin, Nour Y S; Alkhedhairi, Saleh; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar

Disrupting the ASH2L-DPY30 PPI in cancer: structure, function, and therapeutic opportunities in H3K4 methylation

破坏癌症中的ASH2L-DPY30蛋白-蛋白质相互作用:H3K4甲基化中的结构、功能和治疗机会

Kamel, Emadeldin M; Allam, Ahmed A; Rudayni, Hassan A; Alkhedhairi, Saleh; Ahmed, Noha A; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar

Disarming the Hsp70-Bim Alliance: Small-Molecule and Peptidic Disruptors of a Chaperone-Apoptotic Switch in Cancer

解除 Hsp70-Bim 联盟的武装:癌症中分子伴侣-凋亡开关的小分子和肽类干扰剂

Kamel, Emadeldin M; Al-Zharani, Mohammed; Alneghery, Lina M; Ahmed, Noha A; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar

Disrupting the Hsp90-Cdc37 axis: a selective strategy for targeting oncogenic kinases in cancer

破坏Hsp90-Cdc37轴:一种选择性靶向癌症致癌激酶的策略

Kamel, Emadeldin M; Ali, Mohamed A M; Allam, Ahmed A; Ahmed, Noha A; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar

Sustainable leads for hypoxic tumor therapy: allosteric selective inhibition of carbonic anhydrase IX by abietane-type resin acids

乏氧肿瘤治疗的可持续线索:枞烷型树脂酸对碳酸酐酶IX的变构选择性抑制

Kamel, Emadeldin M; Osman, Ali H M; Othman, Sarah I; Abalkhail, Adil; Maodaa, Saleh; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar

Breaking the oncogenic alliance: advances in disrupting the MTDH-SND1 complex for cancer therapy

打破致癌联盟:破坏 MTDH-SND1 复合物用于癌症治疗的进展

Ahmed, Noha A; Allam, Ahmed A; Rudayni, Hassan A; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar; Kamel, Emadeldin M

Entrance-channel plugging by natural sulfonamide antibiotics yields isoform-selective carbonic anhydrase IX inhibitors: an integrated in silico/ in vitro discovery of the lead SB-203207

天然磺胺类抗生素通过堵塞入口通道产生同工型选择性碳酸酐酶IX抑制剂:先导化合物SB-203207的计算机辅助/体外整合发现

Kamel, Emadeldin M; Ahmed, Noha A; Maodaa, Saleh; Abuamarah, Bassam A; Othman, Sarah I; Abalkhail, Adil; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar

Mycosynthesis of zinc oxide nanoparticles using Mucor racemosus with their antimicrobial, antibiofilm, anticancer and antioxidant activities

利用毛霉属真菌合成氧化锌纳米颗粒及其抗菌、抗生物膜、抗癌和抗氧化活性

Elkady, Fathy M; Badr, Bahaa Mohammed; Saied, Ebrahim; Hashem, Amr H; Abdulrahman, Mohammed S; Alkherkhisy, Mohammad M; Selim, Tharwat A; Alshabrmi, Fahad M; Alatawi, Eid A; Aba Alkhayl, Faris F; Salama, Ayman; Mansy, Moselhy S; Aufy, Mohammed

Monotherapy With Immune Checkpoint Inhibitors in Patients With Recurrent and/or Metastatic Sinonasal Squamous Cell Carcinoma

免疫检查点抑制剂单药治疗复发性和/或转移性鼻窦鳞状细胞癌患者

Lein, Alexander; Fuereder, Thorsten; Stoeth, Manuel; Scherzad, Agmal; Hackenberg, Stephan; Schnöll, Julia; Kadletz-Wanke, Lorenz; Heiduschka, Gregor; Jaiswal, Archana; Bhalla, Rajiv; Kenner, Lukas; Brkic, Faris F

Peripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV-2 Infection

SARS-CoV-2感染引起的急性及长期肾功能障碍的外周转录组学研究

Jayaraman, Pushkala; Rajagopal, Madhumitha; Paranjpe, Ishan; Suarez-Farinas, Mayte; Liharska, Lora E; Thompson, Ryan C; Del Valle, Diane Marie; Beckmann, Noam D; Lund, Anina N; Gownivaripally, Pooja; Oh, Wonsuk; Gulamali, Faris F; Kauffman, Justin; Gonzalez-Kozlova, Edgar; Dellepiane, Sergio; Vasquez-Rios, George; Vaid, Akhil; Jiang, Joy; Fox, Ben; Sakhuja, Ankit; Chen, Steven; Kenigsberg, Ephraim; He, John Cijiang; Coca, Steven G; Chan, Lili; Merad, Miram; Kim-Schulze, Seunghee; Gnjatic, Sacha; Tsalik, Ephraim L; Langley, Raymond; Charney, Alexander W; Nadkarni, Girish N