Pharmacological HIF activation protects against diet-induced obesity, glucose intolerance, and skeletal dysfunction by exerting dual beneficial effects on energy metabolism and bone.
药物性 HIF 激活通过对能量代谢和骨骼发挥双重有益作用,防止饮食引起的肥胖、葡萄糖耐受不良和骨骼功能障碍。
期刊:Bone Research
影响因子:15
doi:10.1038/s41413-025-00503-3
Valle-Tenney Roger, Peredo Nicolas, De Samblancx Karen, Nefyodova Elena, Cardoen Ruben, Dehaemers Tom, Farlay Delphine, Chapurlat Roland, Van der Schueren Bart, Mathieu Chantal, Vangoitsenhoven Roman, Maes Christa