日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

TNF alpha unmasks enteric malate aspartate shuttle dysfunction bridging Parkinson disease and intestinal inflammation.

TNF-α 揭示肠道苹果酸天冬氨酸转运功能障碍，从而将帕金森病与肠道炎症联系起来。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-71317-y
Ghirotto Bruno, Gonçalves Luís Eduardo, Ruder Vivien, James Christina, Gerasimova Elizaveta, Rizo Tania, Wend Holger, Farrell Michaela, Gerez Juan Atilio, Prymaczok Natalia Cecilia, Kuijs Merel, Shulman Maiia, Hartebrodt Anne, Prots Iryna, Gessner Arne, Vieth Michael, Zunke Friederike, Winkler Jürgen, Blumenthal David B, Theis Fabian J, Riek Roland, Günther Claudia, Neurath Markus, Gupta Pooja, Winner Beate
帕金森
炎症/感染
TNF
TNF-α
Immunology/Inflammation
炎症
发表日期：2026
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Deciphering brain organoid heterogeneity by identifying key quality determinants.

通过识别关键质量决定因素来解读脑类器官的异质性

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-08855-6
Boerstler Tom, Kachkin Daniil, Gerasimova Elizaveta, Zagha Naime, Furlanetto Federica, Nayebzade Negar, Zappia Luke, Boisvert Michelle, Farrell Michaela, Ploetz Sonja, Prots Iryna, Regensburger Martin, Günther Claudia, Winkler Juergen, Gupta Pooja, Theis Fabian, Karow Marisa, Falk Sven, Winner Beate, Krach Florian
神经科学
3D/类器官
发表日期：2025
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TNF-α disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson's Disease patients.

TNF-α 会破坏苹果酸-天冬氨酸穿梭，从而驱动帕金森病患者 iPSC 衍生的肠神经谱系发生代谢重编程

期刊:
影响因子:
doi:10.1101/2025.03.25.644826
Ghirotto Bruno, Gonçalves Luís Eduardo, Ruder Vivien, James Christina, Gerasimova Elizaveta, Rizo Tania, Wend Holger, Farrell Michaela, Gerez Juan Atilio, Prymaczok Natalia Cecilia, Kuijs Merel, Shulman Maiia, Hartebrodt Anne, Prots Iryna, Gessner Arne, Zunke Friederike, Winkler Jürgen, Blumenthal David B, Theis Fabian J, Riek Roland, Günther Claudia, Neurath Markus, Gupta Pooja, Winner Beate
代谢
神经科学
代谢重编程
发表日期：2025
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Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

iPSC高分辨率基因分析的需求：来自ForIPS联盟的成果和经验教训

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-35506-0
Popp, Bernt; Krumbiegel, Mandy; Grosch, Janina; Sommer, Annika; Uebe, Steffen; Kohl, Zacharias; Plötz, Sonja; Farrell, Michaela; Trautmann, Udo; Kraus, Cornelia; Ekici, Arif B; Asadollahi, Reza; Regensburger, Martin; Günther, Katharina; Rauch, Anita; Edenhofer, Frank; Winkler, Jürgen; Winner, Beate; Reis, André
发表日期：2018
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