日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An exploratory, open-label, randomized, multicenter study to investigate the pharmacodynamics of a glycoengineered antibody (imgatuzumab) and cetuximab in patients with operable head and neck squamous cell carcinoma

一项探索性、开放标签、随机、多中心研究,旨在研究糖基化抗体(imgatuzumab)和西妥昔单抗在可手术头颈部鳞状细胞癌患者中的药效学。

Temam, S; Spicer, J; Farzaneh, F; Soria, J C; Oppenheim, D; McGurk, M; Hollebecque, A; Sarini, J; Hussain, K; Soehrman Brossard, S; Manenti, L; Evers, S; Delmar, P; Di Scala, L; Mancao, C; Feuerhake, F; Andries, L; Ott, M G; Passioukov, A; Delord, J P

Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma

慢病毒诱导的“智能”树突状细胞:用于治疗TRP2阳性黑色素瘤的免疫疗法的药效学和符合GMP规范的生产

Sundarasetty, B S; Chan, L; Darling, D; Giunti, G; Farzaneh, F; Schenck, F; Naundorf, S; Kuehlcke, K; Ruggiero, E; Schmidt, M; von Kalle, C; Rothe, M; Hoon, D S B; Gerasch, L; Figueiredo, C; Koehl, U; Blasczyk, R; Gutzmer, R; Stripecke, R

Glyco-engineered anti-EGFR mAb elicits ADCC by NK cells from colorectal cancer patients irrespective of chemotherapy

糖基化改造的抗EGFR单克隆抗体可诱导结直肠癌患者NK细胞产生抗体依赖性细胞毒性作用(ADCC),且不受化疗影响。

Oppenheim, D E; Spreafico, R; Etuk, A; Malone, D; Amofah, E; Peña-Murillo, C; Murray, T; McLaughlin, L; Choi, B S; Allan, S; Belousov, A; Passioukov, A; Gerdes, C; Umaña, P; Farzaneh, F; Ross, P

Goniothalamin-induced oxidative stress, DNA damage and apoptosis via caspase-2 independent and Bcl-2 independent pathways in Jurkat T-cells

在Jurkat T细胞中,Goniothalamin通过caspase-2非依赖性和Bcl-2非依赖性途径诱导氧化应激、DNA损伤和细胞凋亡

Inayat-Hussain, S H; Chan, K M; Rajab, N F; Din, L B; Chow, S C; Kizilors, A; Farzaneh, F; Williams, G T

PML involvement in the p73-mediated E1A-induced suppression of EGFR and induction of apoptosis in head and neck cancers.

PML参与p73介导的E1A诱导的EGFR抑制和头颈癌细胞凋亡的诱导

Klanrit P, Taebunpakul P, Flinterman M B, Odell E W, Riaz M A, Melino G, Salomoni P, Mymryk J S, Gäken J, Farzaneh F, Tavassoli M

RACK-1 overexpression protects against goniothalamin-induced cell death.

RACK-1 过表达可防止角蛋白诱导的细胞死亡

Inayat-Hussain S H, Wong L T, Chan K M, Rajab N F, Din L B, Harun R, Kizilors A, Saxena N, Mourtada-Maarabouni M, Farzaneh F, Williams G T

p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing

p400 功能是腺病毒 E1A 介导的 EGFR 抑制和肿瘤细胞杀伤所必需的。

Flinterman, M B; Mymryk, J S; Klanrit, P; Yousef, A F; Lowe, S W; Caldas, C; Gäken, J; Farzaneh, F; Tavassoli, M

Efficient retroviral infection of mammalian cells is blocked by inhibition of poly(ADP-ribose) polymerase activity

抑制聚(ADP-核糖)聚合酶活性可阻断逆转录病毒对哺乳动物细胞的有效感染。

Gäken, J A; Tavassoli, M; Gan, S U; Vallian, S; Giddings, I; Darling, D C; Galea-Lauri, J; Thomas, M G; Abedi, H; Schreiber, V; Ménissier-de Murcia, J; Collins, M K; Shall, S; Farzaneh, F

Differences in immune recognition of cytochrome P4502D6 by liver kidney microsomal (LKM) antibody in autoimmune hepatitis and chronic hepatitis C virus infection

自身免疫性肝炎和慢性丙型肝炎病毒感染中肝肾微粒体(LKM)抗体对细胞色素P4502D6的免疫识别差异

Ma, Y; Peakman, M; Lobo-Yeo, A; Wen, L; Lenzi, M; Gäken, J; Farzaneh, F; Mieli-Vergani, G; Bianchi, F B; Vergani, D

c-erbB-2/c-erbA co-amplification indicative of lymph node metastasis, and c-myc amplification of high tumour grade, in human breast carcinoma

在人类乳腺癌中,c-erbB-2/c-erbA 共扩增提示淋巴结转移,而 c-myc 扩增提示肿瘤分级高。

Tavassoli, M; Quirke, P; Farzaneh, F; Lock, N J; Mayne, L V; Kirkham, N