日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Computational design of generalist cyclopropanases with stereodivergent selectivity

具有立体选择性的广谱环丙烷酶的计算设计

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68327-1
Shen, Zhuofan; Siriboe, Mary G; Ren, Xinkun; Dayananda, Thakshila; Jenkins, Jermaine L; Khare, Sagar D; Fasan, Rudi
发表日期：2026
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Highly stereoselective synthesis of allylic β-lactams via enzymatic C(sp(3))-H amidation

通过酶促C(sp(3))-H酰胺化反应高立体选择性合成烯丙基β-内酰胺

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d6sc01440b
Jafari, Nawal Zahra; Wang, Zheyuan; Chattopadhyay, Anwita; Roy, Satyajit; Fasan, Rudi
发表日期：2026
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Photobiocatalytic Enantioselective Benzylic C(sp(3))-H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer.

硫胺素依赖性酶通过分子间氢原子转移实现光生物催化对映选择性苄位 C(sp(3))-H 酰化

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c01642
Lu Yen-Chu, Adukure Ronald D, Roy Satyajit, Chien Derek L, McGill Matthew J, Polara Sarthi, Cisneros G Andrés, Scheidt Karl A, Fasan Rudi
免疫/内分泌
发表日期：2025
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A comprehensive mechanistic investigation of sustainable carbene N-H insertion catalyzed by engineered His-ligated heme proteins

对工程化组氨酸配位血红素蛋白催化的可持续卡宾NH插入反应进行全面的机理研究

期刊:Catalysis Science & Technology
影响因子:4.2
doi:10.1039/d4cy00999a
Khade, Rahul L; Adukure, Ronald Daisuke; Zhao, Xinyi; Wang, Carolyn; Fasan, Rudi; Zhang, Yong
发表日期：2025
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Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases

用于共价捕获和抑制去泛素化酶的内部泛素亲电试剂

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.202500318
Pannala, Nipuni M; Patel, Rishi S; Anit, Abhijith Saseendran; Bhattacharya, Debapriya; Teron, Kristos Negron; Drown, Bryon; Fasan, Rudi; Das, Chittaranjan
泛素化
表观遗传
发表日期：2025
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Biocatalytic strategy for the construction of sp(3)-rich polycyclic compounds from directed evolution and computational modelling

基于定向进化和计算建模的sp(3)富集多环化合物的生物催化构建策略

期刊:Nature Chemistry
影响因子:20.2
doi:10.1038/s41557-023-01435-3
Vargas, David A; Ren, Xinkun; Sengupta, Arkajyoti; Zhu, Ledong; Roy, Satyajit; Garcia-Borràs, Marc; Houk, K N; Fasan, Rudi
发表日期：2024
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Stereodivergent Synthesis of Pyridyl Cyclopropanes via Enzymatic Activation of Pyridotriazoles

通过吡啶并三唑的酶促活化实现吡啶基环丙烷的立体发散合成

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c06103
Roy, Satyajit; Wang, Yining; Zhao, Xinyi; Dayananda, Thakshila; Chu, Jia-Min; Zhang, Yong; Fasan, Rudi
发表日期：2024
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Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library

从多重噬菌体展示文库中筛选靶向SARS-CoV-2程序性核糖体移码RNA的环状肽

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d4sc04026k
Iannuzzelli, Jacob A; Bonn, Rachel; Hong, Andrew S; Anitha, Abhijith Saseendran; Jenkins, Jermaine L; Wedekind, Joseph E; Fasan, Rudi
SARS-CoV-2
发表日期：2024
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Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone

血红素蛋白催化的重氮酮环丙烷化反应的机理多样性

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-43559-7
Nam, Donggeon; Bacik, John-Paul; Khade, Rahul L; Aguilera, Maria Camila; Wei, Yang; Villada, Juan D; Neidig, Michael L; Zhang, Yong; Ando, Nozomi; Fasan, Rudi
发表日期：2023
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Enantioselective Single and Dual α-C-H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer

通过酶促卡宾转移实现环胺的对映选择性单键和双键α-CH键官能化

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.2c10775
Ren, Xinkun; Couture, Bo M; Liu, Ningyu; Lall, Manjinder S; Kohrt, Jeffrey T; Fasan, Rudi
发表日期：2023
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