日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections

利用DNA编码化学库筛选发现强效BET溴结构域1立体选择性抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2122506119
Modukuri, Ram K; Yu, Zhifeng; Tan, Zhi; Ta, Hai Minh; Ucisik, Melek Nihan; Jin, Zhuang; Anglin, Justin L; Sharma, Kiran L; Nyshadham, Pranavanand; Li, Feng; Riehle, Kevin; Faver, John C; Duong, Kevin; Nagarajan, Sureshbabu; Simmons, Nicholas; Palmer, Stephen S; Teng, Mingxing; Young, Damian W; Yi, Joanna S; Kim, Choel; Matzuk, Martin M
发表日期：2022
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Discovery and characterization of bromodomain 2-specific inhibitors of BRDT

BRDT溴结构域2特异性抑制剂的发现与表征

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2021102118
Yu, Zhifeng; Ku, Angela F; Anglin, Justin L; Sharma, Rajesh; Ucisik, Melek Nihan; Faver, John C; Li, Feng; Nyshadham, Pranavanand; Simmons, Nicholas; Sharma, Kiran L; Nagarajan, Sureshbabu; Riehle, Kevin; Kaur, Gundeep; Sankaran, Banumathi; Storl-Desmond, Marta; Palmer, Stephen S; Young, Damian W; Kim, Choel; Matzuk, Martin M
发表日期：2021
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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M(pro) inhibitors.

DNA编码化学技术可快速获得SARS-CoV-2 M(pro)抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2111172118
Chamakuri Srinivas, Lu Shuo, Ucisik Melek Nihan, Bohren Kurt M, Chen Ying-Chu, Du Huang-Chi, Faver John C, Jimmidi Ravikumar, Li Feng, Li Jian-Yuan, Nyshadham Pranavanand, Palmer Stephen S, Pollet Jeroen, Qin Xuan, Ronca Shannon E, Sankaran Banumathi, Sharma Kiran L, Tan Zhi, Versteeg Leroy, Yu Zhifeng, Matzuk Martin M, Palzkill Timothy, Young Damian W
信号转导
新冠
发表日期：2021
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Indoloxytriazines as binding molecules for the JAK2 JH2 pseudokinase domain and its V617F variant

吲哚氧基三嗪类化合物作为JAK2 JH2假激酶结构域及其V617F变体的结合分子

期刊:Tetrahedron Letters
影响因子:1.5
doi:10.1016/j.tetlet.2021.153248
Newton, Ana S; Liosi, Maria-Elena; Henry, Sean P; Deiana, Luca; Faver, John C; Krimmer, Stefan G; Puleo, David E; Schlessinger, Joseph; Jorgensen, William L
JAK/STAT
信号转导
JAK2
发表日期：2021
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Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library

从以蛋白酶为靶点的DNA编码化合物库中发现强效凝血酶抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2005447117
Dawadi, Surendra; Simmons, Nicholas; Miklossy, Gabriella; Bohren, Kurt M; Faver, John C; Ucisik, Melek Nihan; Nyshadham, Pranavanand; Yu, Zhifeng; Matzuk, Martin M
发表日期：2020
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Structure-Guided Identification of DNMT3B Inhibitors

基于结构的DNMT3B抑制剂鉴定

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.0c00011
Newton, Ana S; Faver, John C; Micevic, Goran; Muthusamy, Viswanathan; Kudalkar, Shalley N; Bertoletti, Nicole; Anderson, Karen S; Bosenberg, Marcus W; Jorgensen, William L
发表日期：2020
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C-N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis

DNA偶联（杂）芳基溴化物和氯化物的CN偶联用于DNA编码化学库的合成

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.9b00863
Chen, Ying-Chu; Faver, John C; Ku, Angela F; Miklossy, Gabriella; Riehle, Kevin; Bohren, Kurt M; Ucisik, Melek N; Matzuk, Martin M; Yu, Zhifeng; Simmons, Nicholas
发表日期：2020
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Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries

利用DNA编码化合物库鉴定奥沙西林酶-48碳青霉烯酶抑制剂

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.0c00015
Taylor, Doris Mia; Anglin, Justin; Park, Suhyeorn; Ucisik, Melek N; Faver, John C; Simmons, Nicholas; Jin, Zhuang; Palaniappan, Murugesan; Nyshadham, Pranavanand; Li, Feng; Campbell, James; Hu, Liya; Sankaran, Banumathi; Prasad, B V Venkataram; Huang, Hongbing; Matzuk, Martin M; Palzkill, Timothy
发表日期：2020
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A Mild, DNA-Compatible Nitro Reduction Using B(2)(OH)(4)

一种温和的、与 DNA 兼容的硝基还原反应，使用 B(2)(OH)(4)

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.9b00497
Du, Huang-Chi; Simmons, Nicholas; Faver, John C; Yu, Zhifeng; Palaniappan, Murugesan; Riehle, Kevin; Matzuk, Martin M
发表日期：2019
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Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis

钯催化（杂）芳基卤化物羟基羰基化反应用于DNA编码化学库的合成

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.9b00447
Li, Jian-Yuan; Miklossy, Gabriella; Modukuri, Ram K; Bohren, Kurt M; Yu, Zhifeng; Palaniappan, Murugesan; Faver, John C; Riehle, Kevin; Matzuk, Martin M; Simmons, Nicholas
发表日期：2019
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