日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG

将醛糖还原酶抑制剂和糖尿病神经病变药物依帕司他重新用于治疗先天性糖基化障碍 PMM2-CDG

Sangeetha Iyer, Feba S Sam, Nina DiPrimio, Graeme Preston, Jan Verheijen, Kausalya Murthy, Zachary Parton, Hillary Tsang, Jessica Lao, Eva Morava, Ethan O Perlstein

Drug screens of NGLY1 deficiency in worm and fly models reveal catecholamine, NRF2 and anti-inflammatory-pathway activation as potential clinical approaches

在蠕虫和果蝇模型中对NGLY1缺陷进行药物筛选,揭示了儿茶酚胺、NRF2和抗炎通路激活是潜在的临床治疗方法。

Iyer, Sangeetha; Mast, Joshua D; Tsang, Hillary; Rodriguez, Tamy P; DiPrimio, Nina; Prangley, Madeleine; Sam, Feba S; Parton, Zachary; Perlstein, Ethan O

Yeast Models of Phosphomannomutase 2 Deficiency, a Congenital Disorder of Glycosylation

磷酸甘露糖变位酶 2 缺乏症(一种先天性糖基化障碍)的酵母模型

Jessica P Lao, Nina DiPrimio, Madeleine Prangley, Feba S Sam, Joshua D Mast, Ethan O Perlstein

Fragile X mental retardation protein regulates synaptic and behavioral plasticity to repeated cocaine administration

脆性X染色体智力低下蛋白调节突触和行为对重复可卡因给药的可塑性

Smith, Laura N; Jedynak, Jakub P; Fontenot, Miles R; Hale, Carly F; Dietz, Karen C; Taniguchi, Makoto; Thomas, Feba S; Zirlin, Benjamin C; Birnbaum, Shari G; Huber, Kimberly M; Thomas, Mark J; Cowan, Christopher W