日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In vivo base editing reduces liver cysts in autosomal dominant polycystic kidney disease

体内碱基编辑可减少常染色体显性多囊肾病中的肝囊肿

Ibel, Antonia; Bhardwaj, Rishi; Yilmaz, Duygu Elif; Kong, Shuhan; Wendlinger, Sarah; Cordero, Carlos; Papaioannou, Dimitra; Papazian, Maria; Schönauer, Ria; Meng, Qiyao; Eckardt, Kai-Uwe; Hassan, Fatima; Volpe, Isabel; Klämbt, Verena; Halbritter, Jan; Fedeles, Sorin; Krappitz, Matteus; Kaminski, Michael M

Structurally Similar Mycotoxins Aflatoxin B(1) and Sterigmatocystin Trigger Different and Distinctive High-Resolution Mutational Spectra in Mammalian Cells

结构相似的真菌毒素黄曲霉毒素B1和赭曲霉毒素在哺乳动物细胞中引发不同且独特的高分辨率突变谱

Thongararm, Pennapa; Chancharoen, Marisa; Suwanwong, Nutchapong; Ruchirawat, Somsak; Ruchirawat, Mathuros; Fedeles, Bogdan I; Croy, Robert G; Essigmann, John M

Qualitative Analysis and Comparison of Externally Led Patient-Focused Drug Development Concepts for Autosomal Recessive Polycystic Kidney Disease Against SONG Initiatives

对外部主导的以患者为中心的常染色体隐性多囊肾病药物开发理念与SONG倡议进行定性分析和比较

Soyfer, Belle; Fedeles, Sorin; Ruyle, Wendy; Hoover, Elise; Liebau, Max C; Hartung, Erum A; Dell, Katherine M; Guay-Woodford, Lisa M; Perrone, Ronald D; Oberdhan, Dorothee

5-Chloro-2'-deoxycytidine Induces a Distinctive High-Resolution Mutational Spectrum of Transition Mutations In Vivo

5-氯-2'-脱氧胞苷在体内诱导独特的高分辨率突变谱

Marisa Chancharoen, Zhiyu Yang, Esha D Dalvie, Nina Gubina, Mathuros Ruchirawat, Robert G Croy, Bogdan I Fedeles, John M Essigmann

A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress

一种合成药物通过增加氧化应激促进囊性细胞凋亡,从而改善多囊肾病

Bogdan I Fedeles, Rishi Bhardwaj, Yasunobu Ishikawa, Sakunchai Khumsubdee, Matteus Krappitz, Nina Gubina, Isabel Volpe, Denise C Andrade, Parisa Westergerling, Tobias Staudner, Jake Campolo, Sally S Liu, Ke Dong, Yiqiang Cai, Michael Rehman, Anna-Rachel Gallagher, Somsak Ruchirawat, Robert G Croy, J

XBP1 Activation Reduces Severity of Polycystic Kidney Disease due to a Nontruncating Polycystin-1 Mutation in Mice

XBP1 激活可降低小鼠非截断性多囊蛋白-1 突变导致的多囊肾病的严重程度

Matteus Krappitz, Rishi Bhardwaj, Ke Dong, Tobias Staudner, Duygu Elif Yilmaz, Carlotta Pioppini, Parisa Westergerling, David Ruemmele, Till Hollmann, Thuy Anh Nguyen, Yiqiang Cai, Anna-Rachel Gallagher, Stefan Somlo, Sorin Fedeles

Corrigendum to "WCN23-1242 Genetic interaction between XBP1 and Pkd1 modulates ADPKD progression" [Kidney International Reports Volume 8, Issue 3, Supplement, March 2023, Page S250]

对“WCN23-1242 XBP1 和 Pkd1 之间的基因相互作用调节 ADPKD 进展”的更正 [肾脏国际报告 第 8 卷,第 3 期,增刊,2023 年 3 月,第 S250 页]

Krappitz, M; Pioppini, C; Bhardwaj, R; Duygu, E; Hollmann, T; Somlo, S; Fedeles, S

Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents

环境致癌物 N-亚硝基二甲胺和 SN1 化疗药物引起的突变谱的分子起源

Amanda L Armijo, Pennapa Thongararm, Bogdan I Fedeles, Judy Yau, Jennifer E Kay, Joshua J Corrigan, Marisa Chancharoen, Supawadee Chawanthayatham, Leona D Samson, Sebastian E Carrasco, Bevin P Engelward, James G Fox, Robert G Croy, John M Essigmann

Polycystic Kidney Disease Drug Development: A Conference Report

多囊肾病药物研发:会议报告

Liebau, Max C; Mekahli, Djalila; Perrone, Ronald; Soyfer, Belle; Fedeles, Sorin

7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli

7,8-二氢-8-氧代-1,N6-乙烯基腺嘌呤:一种在DNA中特异性与Hoogsteen配对的胸腺嘧啶类似物,可诱导大肠杆菌发生A→T颠换。

Aralov, Andrey V; Gubina, Nina; Cabrero, Cristina; Tsvetkov, Vladimir B; Turaev, Anton V; Fedeles, Bogdan I; Croy, Robert G; Isaakova, Ekaterina A; Melnik, Denis; Dukova, Svetlana; Ryazantsev, Dmitriy Y; Khrulev, Alexei A; Varizhuk, Anna M; González, Carlos; Zatsepin, Timofei S; Essigmann, John M