Fegan Jamie E相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Meningococcal vaccine 4CMenB elicits a robust cellular immune response that targets but is not consistently protective against Neisseria gonorrhoeae during murine vaginal infection.

脑膜炎球菌疫苗 4CMenB 可引发强烈的细胞免疫反应，但对小鼠阴道感染期间的淋病奈瑟菌并不能持续提供保护

影响因子:3.1

doi:10.1128/msphere.00940-24

Zeppa Joseph J, Fegan Jamie E, Maiello Pauline, Islam Epshita A, Lee Isaac S, Pham Christine, Caruso Laura-Lee, Gray-Owen Scott D

细胞生物学

发表日期：2025

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Rationally designed minimized TbpB confers broad protection against meningococcal infection

合理设计的最小化TbpB可提供针对脑膜炎球菌感染的广泛保护

doi:10.1101/2025.10.30.685603

Islam, Epshita A; Fegan, Jamie E; Cole, Gregory B; Calmettes, Charles; Ng, Dixon; Au, Natalie Y T; Buckwalter, Carolyn M; Ahn, Sang K; Curran, David M; Caruso, Laura-Lee; Schryvers, Anthony B; Moraes, Trevor F; Gray-Owen, Scott D

发表日期：2025

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Structure-based engineering of a nutrient acquisition protein enhances neutralizing antibodies and protection for the development of a gonococcal vaccine.

通过对营养获取蛋白进行结构工程改造，可以增强中和抗体和保护作用，从而开发淋球菌疫苗。

doi:10.1101/2025.11.06.685839

Au Natalie Y T, Zhong En Ze L, Fegan Jamie E, Islam Epshita A, Xu Stacey X, Ng Dixon, Shah Megha, Caruso Laura-Lee, Lai Christine C L, Schryvers Anthony B, Gray-Owen Scott D, Moraes Trevor F

发表日期：2025

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Meningococcal vaccine Bexsero elicits a robust cellular immune response that targets but is not consistently protective against Neisseria gonorrhoeae during murine vaginal infection

脑膜炎球菌疫苗Bexsero可诱导强烈的细胞免疫反应，该反应可靶向淋病奈瑟菌，但在小鼠阴道感染期间并不能始终提供保护。

doi:10.1101/2024.09.08.611931

Zeppa, Joseph J; Fegan, Jamie E; Maiello, Pauline; Islam, Epshita A; Lee, Isaac S; Pham, Christine; Caruso, Laura-Lee; Gray-Owen, Scott D

细胞生物学

免疫/内分泌

发表日期：2024

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Adjuvant-dependent impacts on vaccine-induced humoral responses and protection in preclinical models of nasal and genital colonization by pathogenic Neisseria

佐剂依赖性影响疫苗诱导的体液免疫反应以及致病性奈瑟菌鼻腔和生殖道定植临床前模型中的保护作用

doi:10.1101/2024.09.07.611809

Islam, Epshita A; Fegan, Jamie E; Zeppa, Joseph J; Ahn, Sang K; Ng, Dixon; Currie, Elissa G; Lam, Jessica; Moraes, Trevor F; Gray-Owen, Scott D

免疫/内分泌

发表日期：2024

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Rational selection of TbpB variants elucidates a bivalent vaccine formulation with broad spectrum coverage against Neisseria gonorrhoeae

合理选择TbpB变体可制备出一种对淋病奈瑟菌具有广谱覆盖的二价疫苗。

doi:10.1101/2024.09.07.611798

Fegan, Jamie E; Islam, Epshita A; Curran, David M; Ng, Dixon; Au, Natalie; Currie, Elissa G; Zeppa, Joseph; Lam, Jessica; Schryvers, Anthony B; Moraes, Trevor F; Gray-Owen, Scott D

发表日期：2024

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