LFZ-4-46, a tetrahydroisoquinoline derivative, induces apoptosis and cell cycle arrest via induction of DNA damage and activation of MAPKs pathway in cancer cells
LFZ-4-46 是一种四氢异喹啉衍生物,通过诱导 DNA 损伤和激活癌细胞中的 MAPKs 通路来诱导细胞凋亡和细胞周期停滞
期刊:Anti-Cancer Drugs
影响因子:
doi:10.1097/CAD.0000000000001077
Lili Xu, Guozheng Huang, Zhihui Zhu, Shasha Tian, Yingying Wei, Huanwu Hong, Xiaowei Lu, Ying Li, Feize Liu, Huajun Zhao
信号转导
细胞生物学
肿瘤
肿瘤细胞
Apoptosis
MAPK/ERK