Felix Klaus相关文献与解析，生知库 | 链接生命科学的每一步

Tumor-specific cytosol-penetrating antibodies for antigen- and TME-dependent intracellular cargo delivery.

用于抗原和肿瘤微环境依赖性细胞内货物递送的肿瘤特异性胞质穿透抗体

期刊:Molecular Therapy Oncology

影响因子:5.3

doi:10.1016/j.omton.2024.200931

Dombrowsky Carolin Sophie, Geyer Felix Klaus, Zakharchuk Diana, Kolmar Harald

Computational Prediction of Single-Domain Immunoglobulin Aggregation Propensities Facilitates Discovery and Humanization of Recombinant Nanobodies

单域免疫球蛋白聚集倾向的计算预测有助于重组纳米抗体的发现和人源化

期刊:Antibodies

影响因子:2.7

doi:10.3390/antib14030073

Geyer, Felix Klaus; Borbeck, Julian; Palka, Wiktoria; Zhou, Xueyuan; Takimoto, Jeffrey; Rabinovich, Brian; Reifenhäuser, Bernd; Friedrich, Karlheinz; Kolmar, Harald

Using protein geometry to optimize cytotoxicity and the cytokine window of a ROR1 specific T cell engager

利用蛋白质几何结构优化 ROR1 特异性 T 细胞接合剂的细胞毒性和细胞因子窗口

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2024.1323049

Xueyuan Zhou #, Felix Klaus Geyer #, Dominic Happel, Jeffrey Takimoto, Harald Kolmar, Brian Rabinovich

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1

平衡同时靶向 EGFR 和 PD-L1 的二合一抗体的亲和力和肿瘤细胞结合能力

期刊:Antibodies

影响因子:2.7

doi:10.3390/antib13020036

Harwardt, Julia; Geyer, Felix Klaus; Schoenfeld, Katrin; Baumstark, David; Molkenthin, Vera; Kolmar, Harald

Fuzzy RNA recognition by the Trypanosoma brucei editosome

布氏锥虫编辑体对RNA的模糊识别

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkac357

Leeder, Wolf-Matthias; Geyer, Felix Klaus; Göringer, Hans Ulrich

发表日期：2022

文献求助收藏

Core-Shell DNA-Cholesterol Nanoparticles Exert Lysosomolytic Activity in African Trypanosomes

核壳型 DNA-胆固醇纳米粒子在非洲锥虫中发挥溶酶体溶解活性

期刊:Chembiochem

影响因子:2.6

doi:10.1002/cbic.202200410

Robert Knieß, Wolf-Matthias Leeder, Paul Reißig, Felix Klaus Geyer, H Ulrich Göringer

信号转导

发表日期：2022

文献求助收藏

Novel Autoantibody Signatures in Sera of Patients with Pancreatic Cancer, Chronic Pancreatitis and Autoimmune Pancreatitis: A Protein Microarray Profiling Approach

胰腺癌、慢性胰腺炎和自身免疫性胰腺炎患者血清中新型自身抗体特征：蛋白质微阵列分析方法

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms21072403

Ghassem-Zadeh, Sahar; Hufnagel, Katrin; Bauer, Andrea; Frossard, Jean-Louis; Yoshida, Masaru; Kutsumi, Hiromu; Acha-Orbea, Hans; Neulinger-Muñoz, Matthias; Vey, Johannes; Eckert, Christoph; Strobel, Oliver; Hoheisel, Jörg D; Felix, Klaus

The emerging field of pancreatic tissue engineering: A systematic review and evidence map of scaffold materials and scaffolding techniques for insulin-secreting cells

胰腺组织工程这一新兴领域：胰岛素分泌细胞支架材料及支架技术的系统综述和证据图谱

期刊:Journal of Tissue Engineering

影响因子:7

doi:10.1177/2041731419884708

Salg, Gabriel Alexander; Giese, Nathalia A; Schenk, Miriam; Hüttner, Felix J; Felix, Klaus; Probst, Pascal; Diener, Markus K; Hackert, Thilo; Kenngott, Hannes Götz

C-reactive protein (CRP) promotes malignant properties in pancreatic neuroendocrine neoplasms

C反应蛋白（CRP）促进胰腺神经内分泌肿瘤的恶性转化

期刊:Endocrine Connections

影响因子:2.8

doi:10.1530/EC-19-0132

Schimmack, Simon; Yang, Yongchao; Felix, Klaus; Herbst, Markus; Li, Yixiong; Schenk, Miriam; Bergmann, Frank; Hackert, Thilo; Strobel, Oliver

Targeting highly attenuated IL-18 to PD-1 for enhanced anti-tumor activity.

靶向高度减弱的IL-18至PD-1以增强抗肿瘤活性。

Tumor-specific cytosol-penetrating antibodies for antigen- and TME-dependent intracellular cargo delivery.

用于抗原和肿瘤微环境依赖性细胞内货物递送的肿瘤特异性胞质穿透抗体

Computational Prediction of Single-Domain Immunoglobulin Aggregation Propensities Facilitates Discovery and Humanization of Recombinant Nanobodies

单域免疫球蛋白聚集倾向的计算预测有助于重组纳米抗体的发现和人源化

Using protein geometry to optimize cytotoxicity and the cytokine window of a ROR1 specific T cell engager

利用蛋白质几何结构优化 ROR1 特异性 T 细胞接合剂的细胞毒性和细胞因子窗口

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1

平衡同时靶向 EGFR 和 PD-L1 的二合一抗体的亲和力和肿瘤细胞结合能力

Fuzzy RNA recognition by the Trypanosoma brucei editosome

布氏锥虫编辑体对RNA的模糊识别

Core-Shell DNA-Cholesterol Nanoparticles Exert Lysosomolytic Activity in African Trypanosomes

核壳型 DNA-胆固醇纳米粒子在非洲锥虫中发挥溶酶体溶解活性

Novel Autoantibody Signatures in Sera of Patients with Pancreatic Cancer, Chronic Pancreatitis and Autoimmune Pancreatitis: A Protein Microarray Profiling Approach

胰腺癌、慢性胰腺炎和自身免疫性胰腺炎患者血清中新型自身抗体特征：蛋白质微阵列分析方法

The emerging field of pancreatic tissue engineering: A systematic review and evidence map of scaffold materials and scaffolding techniques for insulin-secreting cells

胰腺组织工程这一新兴领域：胰岛素分泌细胞支架材料及支架技术的系统综述和证据图谱

C-reactive protein (CRP) promotes malignant properties in pancreatic neuroendocrine neoplasms

C反应蛋白（CRP）促进胰腺神经内分泌肿瘤的恶性转化