日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice

TMEM106B 缺失会增强前颗粒蛋白缺乏小鼠的溶酶体和 FTLD 样病理

期刊:EMBO Reports
影响因子:6.5
doi:10.15252/embr.202050241
Georg Werner, Markus Damme, Martin Schludi, Johannes Gnörich, Karin Wind, Katrin Fellerer, Benedikt Wefers, Wolfgang Wurst, Dieter Edbauer, Matthias Brendel, Christian Haass, Anja Capell
信号转导
发表日期：2020
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Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology.

阿尔茨海默病早期脑脊液 sTREM2 的增加与 tau 蛋白相关的神经退行性变有关，但与淀粉样蛋白-β 病理无关

期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-018-0301-5
Suárez-Calvet Marc, Morenas-Rodríguez Estrella, Kleinberger Gernot, Schlepckow Kai, Araque Caballero Miguel Ángel, Franzmeier Nicolai, Capell Anja, Fellerer Katrin, Nuscher Brigitte, Eren Erden, Levin Johannes, Deming Yuetiva, Piccio Laura, Karch Celeste M, Cruchaga Carlos, Shaw Leslie M, Trojanowski John Q, Weiner Michael, Ewers Michael, Haass Christian
神经科学
发表日期：2019
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Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism

PGRN 或 TREM2 缺失时小胶质细胞活化阶段相反，导致脑葡萄糖代谢降低

期刊:EMBO Molecular Medicine
影响因子:9
doi:10.15252/emmm.201809711
Julia K Götzl, Matthias Brendel, Georg Werner, Samira Parhizkar, Laura Sebastian Monasor, Gernot Kleinberger, Alessio-Vittorio Colombo, Maximilian Deussing, Matias Wagner, Juliane Winkelmann, Janine Diehl-Schmid, Johannes Levin, Katrin Fellerer, Anika Reifschneider, Sebastian Bultmann, Peter Bartens
代谢
胶质细胞
发表日期：2019
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Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice

小胶质细胞早期溶酶体成熟缺陷引发前颗粒蛋白基因敲除小鼠其他脑细胞溶酶体活性增强

期刊:Molecular Neurodegeneration
影响因子:14.9
doi:10.1186/s13024-018-0281-5
Julia K Götzl, Alessio-Vittorio Colombo, Katrin Fellerer, Anika Reifschneider, Georg Werner, Sabina Tahirovic, Christian Haass, Anja Capell
细胞生物学
胶质细胞
发表日期：2018
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CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

脑脊液前颗粒蛋白在阿尔茨海默病病程中增加，并与 sTREM2、神经退行性疾病和认知能力下降有关

期刊:EMBO Molecular Medicine
影响因子:9
doi:10.15252/emmm.201809712
Marc Suárez-Calvet, Anja Capell, Miguel Ángel Araque Caballero, Estrella Morenas-Rodríguez, Katrin Fellerer, Nicolai Franzmeier, Gernot Kleinberger, Erden Eren, Yuetiva Deming, Laura Piccio, Celeste M Karch, Carlos Cruchaga, Katrina Paumier, Randall J Bateman, Anne M Fagan, John C Morris, Johannes L
神经
阿尔茨海默症
发表日期：2018
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Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis

前颗粒蛋白相关额颞叶变性和神经元蜡样脂褐素沉积症的常见病理生化特征

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-014-1262-6
Julia K Götzl, Kohji Mori, Markus Damme, Katrin Fellerer, Sabina Tahirovic, Gernot Kleinberger, Jonathan Janssens, Julie van der Zee, Christina M Lang, Elisabeth Kremmer, Jean-Jacques Martin, Sebastiaan Engelborghs, Hans A Kretzschmar, Thomas Arzberger, Christine Van Broeckhoven, Christian Haass, An
神经
发表日期：2014
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Progranulin transcripts with short and long 5' untranslated regions (UTRs) are differentially expressed via posttranscriptional and translational repression

具有短和长5'非翻译区（UTR）的前粒蛋白转录本通过转录后和翻译抑制而差异表达。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M114.560128
Capell, Anja; Fellerer, Katrin; Haass, Christian
发表日期：2014
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Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase

碱化剂和液泡ATPase抑制可挽救与额颞叶变性相关的颗粒蛋白前体缺乏症

期刊:Journal of Neuroscience
影响因子:4.4
doi:10.1523/JNEUROSCI.5757-10.2011
Anja Capell, Sabine Liebscher, Katrin Fellerer, Nathalie Brouwers, Michael Willem, Sven Lammich, Ilse Gijselinck, Tobias Bittner, Aaron M Carlson, Florenz Sasse, Brigitte Kunze, Heinrich Steinmetz, Rolf Jansen, Dorothee Dormann, Kristel Sleegers, Marc Cruts, Jochen Herms, Christine Van Broeckhoven, 
发表日期：2011
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Impact of PsbTc on forward and back electron flow, assembly, and phosphorylation patterns of photosystem II in tobacco

PsbTc对烟草光系统II正向和反向电子传递、组装和磷酸化模式的影响

期刊:Plant Physiology
影响因子:6.9
doi:10.1104/pp.108.126060
Umate, Pavan; Fellerer, Christine; Schwenkert, Serena; Zoryan, Mikael; Eichacker, Lutz A; Sadanandam, Abbagani; Ohad, Itzhak; Herrmann, Reinhold G; Meurer, Jörg
信号转导
磷酸化
发表日期：2008
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Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion

与额颞叶变性相关的前颗粒蛋白基因错义突变，伴有泛素免疫反应性内含物，会减少前颗粒蛋白的产生和分泌

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.M705115200
Sunita S Shankaran, Anja Capell, Alexander T Hruscha, Katrin Fellerer, Manuela Neumann, Bettina Schmid, Christian Haass
免疫
发表日期：2008
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