文献库，生知库 | 链接生命科学的每一步

Antiviral activity and in vitro mutation development pathways of MK-6186, a novel nonnucleoside reverse transcriptase inhibitor

新型非核苷类逆转录酶抑制剂MK-6186的抗病毒活性及体外突变发展途径

期刊:Antimicrobial Agents and Chemotherapy

Meiqing Lu, Peter J Felock, Vandna Munshi, Renee C Hrin, Ying-Jie Wang, Youwei Yan, Sanjeev Munshi, Georgia B McGaughey, Robert Gomez, Neville J Anthony, Theresa M Williams, Jay A Grobler, Daria J Hazuda, Philip M McKenna, Michael D Miller, Ming-Tain Lai

Distinct mutation pathways of non-subtype B HIV-1 during in vitro resistance selection with nonnucleoside reverse transcriptase inhibitors

非核苷类逆转录酶抑制剂体外耐药筛选过程中非亚型 B HIV-1 的不同突变途径

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.1

doi:10.1128/AAC.00829-10

Ming-Tain Lai, Meiqing Lu, Peter J Felock, Renee C Hrin, Ying-Jie Wang, Youwei Yan, Sanjeev Munshi, Georgia B McGaughey, Robert M Tynebor, Thomas J Tucker, Theresa M Williams, Jay A Grobler, Daria J Hazuda, Philip M McKenna, Michael D Miller

Differential divalent cation requirements uncouple the assembly and catalytic reactions of human immunodeficiency virus type 1 integrase

不同的二价阳离子需求使人类免疫缺陷病毒1型整合酶的组装和催化反应解耦联

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.71.9.7005-7011.1997

Hazuda, D J; Felock, P J; Hastings, J C; Pramanik, B; Wolfe, A L

Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds

结构各异的化合物对半位点和全位点逆转录病毒链转移反应的抑制作用相当

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.71.1.807-811.1997

Hazuda, D; Felock, P; Hastings, J; Pramanik, B; Wolfe, A; Goodarzi, G; Vora, A; Brackmann, K; Grandgenett, D

微生物学

发表日期：1997

文献求助收藏

The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates

锰在促进人类免疫缺陷病毒1型整合酶在固定化长末端重复序列底物上形成具有催化活性的复合物的多聚化和组装中的作用

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.70.3.1424-1432.1996

Wolfe, A L; Felock, P J; Hastings, J C; Blau, C U; Hazuda, D J

The Impact of Positive Fluid Balance on Sepsis Subtypes: A Causal Inference Study

正性液体平衡对脓毒症亚型的影响：一项因果推断研究

Rescue of Tolerant CD8+ T Cells during Cancer Immunotherapy with IL2:Antibody Complexes

IL2：抗体复合物在癌症免疫治疗期间拯救耐受性 CD8+ T 细胞

Antiviral activity and in vitro mutation development pathways of MK-6186, a novel nonnucleoside reverse transcriptase inhibitor

新型非核苷类逆转录酶抑制剂MK-6186的抗病毒活性及体外突变发展途径

Distinct mutation pathways of non-subtype B HIV-1 during in vitro resistance selection with nonnucleoside reverse transcriptase inhibitors

非核苷类逆转录酶抑制剂体外耐药筛选过程中非亚型 B HIV-1 的不同突变途径

Differential divalent cation requirements uncouple the assembly and catalytic reactions of human immunodeficiency virus type 1 integrase

不同的二价阳离子需求使人类免疫缺陷病毒1型整合酶的组装和催化反应解耦联

Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds

结构各异的化合物对半位点和全位点逆转录病毒链转移反应的抑制作用相当

The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates

锰在促进人类免疫缺陷病毒1型整合酶在固定化长末端重复序列底物上形成具有催化活性的复合物的多聚化和组装中的作用