日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Liver X receptors are required for thymic resilience and T cell output

肝X受体是胸腺恢复能力和T细胞输出所必需的。

Chan, Christopher T; Fenn, Ashley M; Harder, Nina K; Mindur, John E; McAlpine, Cameron S; Patel, Jyoti; Valet, Colin; Rattik, Sara; Iwamoto, Yoshiko; He, Shun; Anzai, Atsushi; Kahles, Florian; Poller, Wolfram C; Janssen, Henrike; Wong, Lai Ping; Fernandez-Hernando, Carlos; Koolbergen, David R; van der Laan, Anja M; Yvan-Charvet, Laurent; Sadreyev, Ruslan I; Nahrendorf, Matthias; Westerterp, Marit; Tall, Alan R; Gustafsson, Jan-Ake; Swirski, Filip K

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease

肠道上皮内T细胞调节代谢并加速心血管疾病

He, Shun; Kahles, Florian; Rattik, Sara; Nairz, Manfred; McAlpine, Cameron S; Anzai, Atsushi; Selgrade, Daniel; Fenn, Ashley M; Chan, Christopher T; Mindur, John E; Valet, Colin; Poller, Wolfram C; Halle, Lennard; Rotllan, Noemi; Iwamoto, Yoshiko; Wojtkiewicz, Gregory R; Weissleder, Ralph; Libby, Peter; Fernández-Hernando, Carlos; Drucker, Daniel J; Nahrendorf, Matthias; Swirski, Filip K

Cognitive deficits develop 1month after diffuse brain injury and are exaggerated by microglia-associated reactivity to peripheral immune challenge

弥漫性脑损伤后1个月会出现认知功能障碍,并且小胶质细胞对周围免疫刺激的反应会加剧这些障碍。

Muccigrosso, Megan M; Ford, Joni; Benner, Brooke; Moussa, Daniel; Burnsides, Christopher; Fenn, Ashley M; Popovich, Phillip G; Lifshitz, Jonathan; Walker, Fredrick Rohan; Eiferman, Daniel S; Godbout, Jonathan P

Methylene blue attenuates traumatic brain injury-associated neuroinflammation and acute depressive-like behavior in mice

亚甲蓝可减轻小鼠创伤性脑损伤相关的神经炎症和急性抑郁样行为。

Fenn, Ashley M; Skendelas, John P; Moussa, Daniel N; Muccigrosso, Megan M; Popovich, Phillip G; Lifshitz, Jonathan; Eiferman, Daniel S; Godbout, Jonathan P

Immune activation promotes depression 1 month after diffuse brain injury: a role for primed microglia

免疫激活促进弥漫性脑损伤后1个月的抑郁症:启动的小胶质细胞发挥作用

Fenn, Ashley M; Gensel, John C; Huang, Yan; Popovich, Phillip G; Lifshitz, Jonathan; Godbout, Jonathan P

TGFβ produced by IL-10 redirected astrocytes attenuates microglial activation.

IL-10 重定向星形胶质细胞产生的 TGFβ 可减弱小胶质细胞活化

Norden Diana M, Fenn Ashley M, Dugan Allison, Godbout Jonathan P

Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice.

老年小鼠小胶质细胞中脂多糖诱导的白细胞介素 (IL)-4 受体-α 表达以及对 IL-4 促进 M2 效应的相应敏感性受损

Fenn Ashley M, Henry Christopher J, Huang Yan, Dugan Allison, Godbout Jonathan P

Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice

外周固有免疫刺激会加剧小胶质细胞活化,增加中枢神经系统炎症巨噬细胞的数量,并延长社交挫败小鼠的社交退缩行为。

Wohleb, Eric S; Fenn, Ashley M; Pacenta, Ann M; Powell, Nicole D; Sheridan, John F; Godbout, Jonathan P