日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exploring the potential of liver microphysiological systems of varied configurations to model cholestatic chemical effects.

探索不同配置的肝脏微生理系统在模拟胆汁淤积化学效应方面的潜力。

Nitsche Katharina S, Sakolish Courtney, Carmichael Paul L, Hewitt Philip, Bajaj Piyush, Ferguson Stephen S, Lloyd Sarah M, Wilson Sarah S, Bouwmeester Hans, Rusyn Ivan

An in vitro-in silico workflow for predicting renal clearance of environmental chemicals and drugs.

用于预测环境化学物质和药物肾脏清除率的体外-计算机模拟工作流程。

Sakolish Courtney, Lin Hsing-Chieh, Moyer Haley L, Ford Lucie C, Christen Charles H, Wetmore Barbara A, DeVito Michael J, Hewitt Philip, Ferguson Stephen S, Raad Farah, Rusyn Ivan, Chiu Weihsueh A

Comparative investigation of the potential of glyphosate and glyphosate-based formulations to cause oxidative stress and DNA damage in human skin and liver cell systems.

对草甘膦和草甘膦制剂在人体皮肤和肝细胞系统中引起氧化应激和DNA损伤的潜力进行比较研究。

Smith-Roe Stephanie L, DeVito Michael J, Co Caroll, Ramaiahgari Sreenivasa C, Easterling Michael, Rice Julie R, Dunlap Paul E, Crizer David M, Zhou Zhifeng, Merrick Bruce Alex, Xie Guanhua, Harris Shawn F, Shockley Keith R, Tandon Arpit, Oktay Ayse, Mav Deepak, Shah Ruchir, Borrel Alexandre, Gombar Vijay, Masten Scott A, Paules Richard S, Ferguson Stephen S

Oxysterol-binding protein ORP6 regulates lipid metabolism and brain Aβ production.

氧固醇结合蛋白 ORP6 调节脂质代谢和脑 Aβ 生成。

Kasongo Arlette A, Vijithakumar Viyashini, Abd-Elrahman Khaled S, Prabhune Radhika, Gharibeh Lara, Nadeau Rachel, Robillard Isabelle, Spring Shoshana, Robichaud Sabrina, Asif Shaza, Gibbings Derrick, Moore Kathryn J, Sled John G, Ruiz Matthieu, Lavallée-Adam Mathieu, Ferguson Stephen S G, Lacoste Baptiste, Lagace Diane C, Ouimet Mireille

Comparative analysis of Caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability.

在基于凝胶和膜的肠道通透性屏障模型中,对 Caco-2 细胞和人空肠及十二指肠类器官衍生细胞进行比较分析

Moyer Haley L, Vergara Leoncio, Stephan Clifford, Sakolish Courtney, Ford Lucie C, Tsai Han-Hsuan D, Lin Hsing-Chieh, Chiu Weihsueh A, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Rusyn Ivan

Comparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform.

在 PhysioMimix T12 平台上,对不同来源的肾近端小管细胞在静态和流体条件下的生理和转运功能进行比较分析

Sakolish Courtney, Moyer Haley L, Tsai Han-Hsuan D, Ford Lucie C, Dickey Allison N, Bajaj Piyush, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Stanko Jason, Rusyn Ivan

Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity.

肾近端小管细胞来源在肾近端小管毒性体外研究中的比较分析

Sakolish Courtney, Tsai Han-Hsuan D, Lin Hsing-Chieh, Bajaj Piyush, Villenave Remi, Ferguson Stephen S, Stanko Jason P, Becker Richard A, Hewitt Philip, Chiu Weihsueh A, Rusyn Ivan

Human Small Intestinal Tissue Models to Assess Barrier Permeability: Comparative Analysis of Caco-2 Cells, Jejunal and Duodenal Enteroid-Derived Cells, and EpiIntestinal(TM) Tissues in Membrane-Based Cultures with and Without Flow.

人类小肠组织模型评估屏障通透性:在有无流动条件下,对 Caco-2 细胞、空肠和十二指肠类器官衍生细胞以及 EpiIntestinal(TM) 组织在膜基培养中的比较分析

Moyer Haley L, Vergara Leoncio, Stephan Clifford, Sakolish Courtney, Lin Hsing-Chieh, Chiu Weihsueh A, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Rusyn Ivan

Integration of computational models to predict botanical phytochemical constituent clearance routes by the Extended Clearance Classification System (ECCS)

利用扩展清除分类系统(ECCS)整合计算模型预测植物化学成分清除途径

Liu, Yitong; Lawless, Michael; Roe, Amy L; Ferguson, Stephen S

Application of cytochrome P450 enzyme assays to predict p53 inducers and AChE inhibitors that require metabolic activation

应用细胞色素P450酶活性测定预测需要代谢活化的p53诱导剂和AChE抑制剂

Ngan, Deborah K; Sakamuru, Srilatha; Zhao, Jinghua; Xia, Menghang; Ferguson, Stephen S; Reif, David M; Simeonov, Anton; Huang, Ruili