日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs

锥蝽在从吸血昆虫转变为吸血昆虫的过程中,其毒液发生了适应性改变和进化。

Christina N Zdenek ,Fernanda C Cardoso ,Samuel D Robinson ,Raine S Mercedes ,Enriko R Raidjõe ,María José Hernandez-Vargas ,Jiayi Jin ,Gerardo Corzo ,Irina Vetter ,Glenn F King ,Bryan G Fry ,Andrew A Walker

Inhibition of N-type calcium channels by phenoxyaniline and sulfonamide analogues

苯氧苯胺和磺酰胺类似物对 N 型钙通道的抑制

Anjie S Bispat, Fernanda C Cardoso, Md Mahadhi Hasan, Yashad Dongol, Ricki Wilcox, Richard J Lewis, Peter J Duggan, Kellie L Tuck

High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms

高内涵荧光生物测定研究毒液诱导的孔隙形成、离子通道调节和细胞膜裂解

Simon Kramer, Charan Kotapati, Yuanzhao Cao, Bryan G Fry, Nathan J Palpant, Glenn F King, Fernanda C Cardoso

The T-type calcium channel Ca V 3.2 regulates bladder afferent responses to mechanical stimuli

型钙通道 Ca V 3.2 调节膀胱对机械刺激的传入反应

Luke Grundy, Cindy Tay, Stewart Christie, Andrea M Harrington, Joel Castro, Fernanda C Cardoso, Richard J Lewis, Vladimir Zagorodnyuk, Stuart M Brierley

The Deadly Toxin Arsenal of the Tree-Dwelling Australian Funnel-Web Spiders

澳大利亚树栖漏斗网蜘蛛的致命毒素库

Fernanda C Cardoso, Sandy S Pineda, Volker Herzig, Kartik Sunagar, Naeem Yusuf Shaikh, Ai-Hua Jin, Glenn F King, Paul F Alewood, Richard J Lewis, Sébastien Dutertre

Pharmacological Inhibition of the Voltage-Gated Sodium Channel NaV1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

电压门控钠通道 NaV1.7 的药理学抑制可缓解肠易激综合征啮齿动物模型中的慢性内脏痛

Yan Jiang, Joel Castro, Linda V Blomster, Akello J Agwa, Jessica Maddern, Gudrun Schober, Volker Herzig, Chun Yuen Chow, Fernanda C Cardoso, Paula Demétrio De Souza França, Junior Gonzales, Christina I Schroeder, Steffen Esche, Thomas Reiner, Stuart M Brierley, Glenn F King

Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain

三环抗抑郁药对 N 型钙离子通道的抑制 - 其用于治疗神经性疼痛的实验和理论依据

Fernanda C Cardoso, Matthieu Schmit, Michael J Kuiper, Richard J Lewis, Kellie L Tuck, Peter J Duggan

Two for the Price of One: Heterobivalent Ligand Design Targeting Two Binding Sites on Voltage-Gated Sodium Channels Slows Ligand Dissociation and Enhances Potency

一物两用:针对电压门控钠通道上两个结合位点的异二价配体设计可减缓配体解离并增强药效

Alicia Peschel, Fernanda C Cardoso, Andrew A Walker, Thomas Durek, M Rhia L Stone, Nayara Braga Emidio, Philip E Dawson, Markus Muttenthaler, Glenn F King

Characterisation of d-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator

d-芋螺毒素 TxVIA 作为哺乳动物 T 型钙通道调节剂的表征

Dan Wang, S W A Himaya, Jean Giacomotto, Md Mahadhi Hasan, Fernanda C Cardoso, Lotten Ragnarsson, Richard J Lewis

'Messy' Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency

χ-芋螺毒素 MrIA 的“混乱”加工产生了 hNET 效力降低的同源物

Rebekah Ziegman, Andreas Brust, Prerna Jha, Fernanda C Cardoso, Richard J Lewis, Paul F Alewood