Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo
纳米抗体可有效调节 CD38 的酶活性,并允许在小鼠模型中对 CD38+ 肿瘤进行体内特异性成像
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-017-14112-6
William Fumey, Julia Koenigsdorf, Valentin Kunick, Stephan Menzel, Kerstin Schütze, Mandy Unger, Levin Schriewer, Friedrich Haag, Gerhard Adam, Anna Oberle, Mascha Binder, Ralf Fliegert, Andreas Guse, Yong Juan Zhao, Hon Cheung Lee, Fabio Malavasi, Fernando Goldbaum, Rob van Hegelsom, Catelijne Stor