日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification of a series of pyrrolo-pyrimidine-based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication

鉴定出一系列基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂，这些抑制剂能够抑制冠状病毒的复制

期刊:mBio
影响因子:4.7
doi:10.1128/mbio.03865-24
Pfannenstiel, Jessica J; Duong, Men Thi Hoai; Cluff, Daniel; Sherrill, Lavinia M; Colquhoun, Iain; Cadoux, Gabrielle; Thorne, Devyn; Pääkkönen, Johan; Schemmel, Nathaniel F; O'Connor, Joseph; Saenjamsai, Pradtahna; Feng, Mei; Parthasarathy, Srivatsan; Hageman, Michael J; Johnson, David K; Roy, Anuradha; Lehtiö, Lari; Ferraris, Dana V; Fehr, Anthony R
微生物学
SARS-CoV-2
发表日期：2025
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Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target.

发现靶向 SARS-CoV-2 Mac1 并抑制冠状病毒复制的 2-酰胺-3-甲基酯噻吩类化合物，验证 Mac1 作为抗病毒靶点

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c02451
Wazir Sarah, Parviainen Tomi A O, Pfannenstiel Jessica J, Duong Men Thi Hoai, Cluff Daniel, Sowa Sven T, Galera-Prat Albert, Ferraris Dana, Maksimainen Mirko M, Fehr Anthony R, Heiskanen Juha P, Lehtiö Lari
炎症/感染
新冠
Viral
发表日期：2024
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Identification of a series of pyrrolo-pyrimidine based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication.

鉴定出一系列基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂，这些抑制剂能够抑制冠状病毒的复制

期刊:
影响因子:
doi:10.1101/2024.10.28.620664
Pfannenstiel Jessica J, Duong Men Thi Hoai, Cluff Daniel, Sherrill Lavania M, Colquhoun Iain, Cadoux Gabrielle, Thorne Devyn, Pääkkönen Johan, Schemmel Nathaniel F, O'Connor Joseph, Saenjamsai Pradtahna, Feng Mei, Hageman Michael J, Johnson David K, Roy Anuradha, Lehtiö Lari, Ferraris Dana V, Fehr Anthony R
信号转导
新冠
发表日期：2024
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D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II

D-多巴是一种强效、口服生物利用度高的谷氨酸羧肽酶II变构抑制剂。

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics14102018
Gori, Sadakatali S; Thomas, Ajit G; Pal, Arindom; Wiseman, Robyn; Ferraris, Dana V; Gao, Run-Duo; Wu, Ying; Alt, Jesse; Tsukamoto, Takashi; Slusher, Barbara S; Rais, Rana
发表日期：2022
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Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening.

利用高通量筛选发现抑制SARS-CoV-2 Mac1-ADP-核糖结合的化合物

期刊:Antiviral Research
影响因子:4
doi:10.1016/j.antiviral.2022.105344
Roy Anu, Alhammad Yousef M, McDonald Peter, Johnson David K, Zhuo Junlin, Wazir Sarah, Ferraris Dana, Lehtiö Lari, Leung Anthony K L, Fehr Anthony R
信号转导
新冠
发表日期：2022
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Integrating DNA-encoded chemical libraries with virtual combinatorial library screening: Optimizing a PARP10 inhibitor

将DNA编码的化学库与虚拟组合文库筛选相结合：优化PARP10抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2020.127464
Lemke, Mike; Ravenscroft, Hannah; Rueb, Nicole J; Kireev, Dmitri; Ferraris, Dana; Franzini, Raphael M
PARP
PARP1
发表日期：2020
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Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors

氨基甲酸酯类抑制剂对谷氨酸羧肽酶II强效抑制的结构和计算基础

期刊:Bioorganic & Medicinal Chemistry
影响因子:3
doi:10.1016/j.bmc.2018.11.022
Barinka, Cyril; Novakova, Zora; Hin, Niyada; Bím, Daniel; Ferraris, Dana V; Duvall, Bridget; Kabarriti, Gabriel; Tsukamoto, Reiji; Budesinsky, Milos; Motlova, Lucia; Rojas, Camilo; Slusher, Barbara S; Rokob, Tibor András; Rulíšek, Lubomír; Tsukamoto, Takashi
发表日期：2019
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Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cells

双氮丙啶二聚萘醌的合成、表征及其抗肿瘤活性——一类对急性髓系白血病细胞具有强效活性的新型化合物

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2016.11.045
Carter-Cooper, Brandon A; Fletcher, Steven; Ferraris, Dana; Choi, Eun Yong; Kronfli, Dahlia; Dash, Smaraki; Truong, Phuc; Sausville, Edward A; Lapidus, Rena G; Emadi, Ashkan
白血病
细胞生物学
肿瘤
肿瘤免疫
发表日期：2017
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D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold

基于5-羟基-1,2,4-三嗪-6(1H)-酮骨架的D-氨基酸氧化酶抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2016.02.068
Hin, Niyada; Duvall, Bridget; Berry, James F; Ferraris, Dana V; Rais, Rana; Alt, Jesse; Rojas, Camilo; Slusher, Barbara S; Tsukamoto, Takashi
发表日期：2016
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δ-Thiolactones as prodrugs of thiol-based glutamate carboxypeptidase II (GCPII) inhibitors

δ-硫代内酯作为硫醇类谷氨酸羧肽酶II（GCPII）抑制剂的前药

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm401703a
Ferraris, Dana V; Majer, Pavel; Ni, Chiyou; Slusher, C Ethan; Rais, Rana; Wu, Ying; Wozniak, Krystyna M; Alt, Jesse; Rojas, Camilo; Slusher, Barbara S; Tsukamoto, Takashi
发表日期：2014
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