日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neoantigen-specific T cell help outperforms non-specific help in multi-antigen DNA vaccination against cancer

在针对癌症的多抗原DNA疫苗接种中,新抗原特异性T细胞辅助优于非特异性辅助。

Joanna Fréderique de Graaf ,Tamara Pesic ,Felicia S Spitzer ,Koen Oosterhuis ,Marcel G M Camps ,Iris Zoutendijk ,Bram Teunisse ,Wahwah Zhu ,Tsolere Arakelian ,Gerben C Zondag ,Ramon Arens ,Jeroen van Bergen ,Ferry Ossendorp

Genome-wide CRISPR screens define determinants of epithelial-mesenchymal transition mediated immune evasion by pancreatic cancer cells

全基因组 CRISPR 筛选确定胰腺癌细胞上皮-间质转化介导免疫逃避的决定因素

Yuanzhuo Gu, Zhengkui Zhang, Marcel G M Camps, Ferry Ossendorp, Ruud H Wijdeven, Peter Ten Dijke

OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum

OX40激动剂通过改变细胞毒性T细胞的分化谱来增强PD-L1检查点阻断作用。

Tetje C van der Sluis ,Guillaume Beyrend ,Esmé T I van der Gracht ,Tamim Abdelaal ,Simon P Jochems ,Robert A Belderbos ,Thomas H Wesselink ,Suzanne van Duikeren ,Floortje J van Haften ,Anke Redeker ,Laura F Ouboter ,Elham Beyranvand Nejad ,Marcel Camps ,Kees L M C Franken ,Margot M Linssen ,Peter Hohenstein ,Noel F C C de Miranda ,Hailiang Mei ,Adriaan D Bins ,John B A G Haanen ,Joachim G Aerts ,Ferry Ossendorp ,Ramon Arens

Effective combination of liposome-targeted chemotherapy and PD-L1 blockade of murine colon cancer

脂质体靶向化疗与 PD-L1 阻断对小鼠结肠癌的有效联合治疗

Zili Gu, Candido G Da Silva, Yang Hao, Timo Schomann, Marcel G M Camps, K van der Maaden, Qi Liu, Ferry Ossendorp, Luis J Cruz

Immune checkpoint inhibition combined with targeted therapy using a novel virus-like drug conjugate induces complete responses in a murine model of local and distant tumors

免疫检查点抑制与使用新型病毒样药物偶联物的靶向治疗相结合,可在小鼠局部和远处肿瘤模型中诱导完全缓解

Ruben V Huis In 't Veld, Sen Ma, Rhonda C Kines, Anneli Savinainen, Cadmus Rich, Ferry Ossendorp, Martine J Jager

M1-derived extracellular vesicles enhance photodynamic therapy and promote immunological memory in preclinical models of colon cancer

M1 衍生的细胞外囊泡可增强光动力疗法并在结肠癌临床前模型中促进免疫记忆

Ruben V Huis In 't Veld, Pablo Lara, Martine J Jager, Roman I Koning, Ferry Ossendorp, Luis J Cruz

Lipid A analog CRX-527 conjugated to synthetic peptides enhances vaccination efficacy and tumor control

脂质A类似物CRX-527与合成肽偶联可增强疫苗接种效果和肿瘤控制能力

Elena Tondini # ,Niels R M Reintjens # ,Giulia Castello ,Tsolere Arakelian ,Marjolein Isendoorn ,Marcel Camps ,Jana Vree ,Gijs A van der Marel ,Dmitri V Filippov ,Jeroen D C Codee ,Ferry Ossendorp

Bacterial Cellulose as Drug Delivery System for Optimizing Release of Immune Checkpoint Blocking Antibodies

细菌纤维素作为药物输送系统优化免疫检查点阻断抗体的释放

Chih Kit Chung, Uwe Beekmann, Dana Kralisch, Katja Bierau, Alan Chan, Ferry Ossendorp, Luis J Cruz

Zinc-Phthalocyanine-Loaded Extracellular Vesicles Increase Efficacy and Selectivity of Photodynamic Therapy in Co-Culture and Preclinical Models of Colon Cancer

载有锌酞菁的细胞外囊泡可提高结肠癌共培养和临床前模型中光动力疗法的疗效和选择性

Pablo Lara, Ruben V Huis In 't Veld, Carla Jorquera-Cordero, Alan B Chan, Ferry Ossendorp, Luis J Cruz

Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides

来自可结合脂质 A 类似物和合成长肽的自辅助癌症疫苗

Niels R M Reintjens, Elena Tondini, Ana R de Jong, Nico J Meeuwenoord, Fabrizio Chiodo, Evert Peterse, Herman S Overkleeft, Dmitri V Filippov, Gijsbert A van der Marel, Ferry Ossendorp, Jeroen D C Codée