日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation

从成功到成功上市:精准发现和开发咪唑并嘧啶 TLR7/8 激动剂佐剂配方

Dheeraj Soni, Francesco Borriello, David A Scott, Frederic Feru, Maria DeLeon, Spencer E Brightman, Wing Ki Cheng, Gandolina Melhem, Jennifer A Smith, Juan C Ramirez, Soumik Barman, Michael Cameron, Aisling Kelly, Kristina Walker, Etsuro Nanishi, Simon Daniel van Haren, Tony Phan, Yizhi Qi, Robert K

Tilting the Scales toward EGFR Mutant Selectivity: Expanding the Scope of Bivalent "Type V" Kinase Inhibitors

向EGFR突变体选择性倾斜:扩大二价“V型”激酶抑制剂的范围

Wittlinger, Florian; Chitnis, Surbhi P; Pham, Calvin D; Damghani, Tahereh; Patel, Kishan B; Möllers, Mareike; Schaeffner, Ilse K; Abidakun, Omobolanle A; Deng, Matthew Q; Ogboo, Blessing C; Rasch, Alexander; Beyett, Tyler S; Buckley, Brian; Feru, Frederic; Shaurova, Tatiana; Knappe, Cornelius; Eck, Michael J; Hershberger, Pamela A; Scott, David A; Brandt, Asher L; Laufer, Stefan A; Heppner, David E

Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC

喹唑啉酮类药物作为变构第四代EGFR抑制剂用于治疗非小细胞肺癌

Gero, Thomas W; Heppner, David E; Beyett, Tyler S; To, Ciric; Azevedo, Seth C; Jang, Jaebong; Bunnell, Thomas; Feru, Frederic; Li, Zhengnian; Shin, Bo Hee; Soroko, Kara M; Gokhale, Prafulla C; Gray, Nathanael S; Jänne, Pasi A; Eck, Michael J; Scott, David A

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

探索致癌基因KRASG12C的靶向降解策略

Mei Zeng, Yuan Xiong, Nozhat Safaee, Radosław P Nowak, Katherine A Donovan, Christine J Yuan, Behnam Nabet, Thomas W Gero, Frederic Feru, Lianbo Li, Sudershan Gondi, Lincoln J Ombelets, Chunshan Quan, Pasi A Jänne, Milka Kostic, David A Scott, Kenneth D Westover, Eric S Fischer, Nathanael S Gray

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

强效、选择性的 KRAS G12C 共价喹唑啉抑制剂

Mei Zeng, Jia Lu, Lianbo Li, Frederic Feru, Chunshan Quan, Thomas W Gero, Scott B Ficarro, Yuan Xiong, Chiara Ambrogio, Raymond M Paranal, Marco Catalano, Jay Shao, Kwok-Kin Wong, Jarrod A Marto, Eric S Fischer, Pasi A Jänne, David A Scott, Kenneth D Westover, Nathanael S Gray

Tetrastatin, the NC1 domain of the α4(IV) collagen chain: a novel potent anti-tumor matrikine

Tetrastatin,α4(IV)胶原链的 NC1 结构域:一种新型强效抗肿瘤基质蛋白

Sylvie Brassart-Pasco, Karine Sénéchal, Jessica Thevenard, Laurent Ramont, Jérome Devy, Ludivine Di Stefano, Aurélie Dupont-Deshorgue, Stéphane Brézillon, Jezabel Feru, Jean-François Jazeron, Marie-Danièle Diebold, Sylvie Ricard-Blum, François-Xavier Maquart, Jean Claude Monboisse