Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction
抗肿瘤IgE抗体MOv18诱导卵巢癌患者巨噬细胞发生过度炎症性极化，从而限制了免疫抑制性巨噬细胞与Treg细胞的相互作用。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-57870-y
Osborn, Gabriel; López-Abente, Jacobo; Adams, Rebecca; Laddach, Roman; Grandits, Melanie; Bax, Heather J; Chauhan, Jitesh; Pellizzari, Giulia; Nakamura, Mano; Stavraka, Chara; Chenoweth, Alicia; Palhares, Lais C G F; Evan, Theodore; Lim, Jessica Hui Cheah; Gross, Amanda; Moise, Lenny; Jatiani, Shashi; Figini, Mariangela; Bianchini, Rodolfo; Jensen-Jarolim, Erika; Ghosh, Sharmistha; Montes, Ana; Sayasneh, Ahmad; Kristeleit, Rebecca; Tsoka, Sophia; Spicer, James; Josephs, Debra H; Karagiannis, Sophia N
巨噬细胞
肿瘤
炎症
T细胞
肿瘤免疫
炎症/感染
巨噬细胞
卵巢癌
Treg
细胞生物学
免疫/内分泌
