日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A high-throughput biocatalytic platform for screening isomeric kainoid natural products

用于筛选异构体红藻氨酸天然产物的高通量生物催化平台

Shepherd, Robert A; Ramachandra, Manasa; Hopiavuori, Austin R; Jones, Melanie C; Fihn, Conrad A; Tabag, Alex J; Manjunath, Ananya; Gad, Limar Y; Whipple, Chloe R; McKinnie, Shaun M K; Sanchez, Laura M

Development of covalent inhibitors for bacterial histidine kinases

开发细菌组氨酸激酶共价抑制剂

Rodriguez, Patricia D; Fihn, Conrad A; Goswami, Manibarsha; Carlson, Erin E

'Need for speed: high throughput' - mass spectrometry approaches for high-throughput directed evolution screening of natural product enzymes

“速度需求:高通量”——用于天然产物酶高通量定向进化筛选的质谱方法

Shepherd, Robert A; Fihn, Conrad A; Tabag, Alex J; McKinnie, Shaun M K; Sanchez, Laura M

A High-Throughput Biocatalytic Platform for Screening Isomeric Kainoid Natural Products

用于筛选异构体红藻氨酸类天然产物的高通量生物催化平台

Shepherd, Robert A; Ramachandra, Manasa; Hopiavuori, Austin R; Jones, Melanie C; Fihn, Conrad A; Tabag, Alex J; Manjunath, Ananya; Gad, Limar Y; Whipple, Chloe R; McKinnie, Shaun M K; Sanchez, Laura M

Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa.

评估扩展的 2-氨基苯并噻唑化合物库作为模型组氨酸激酶抑制剂和铜绿假单胞菌毒力抑制剂的活性

Fihn Conrad A, Lembke Hannah K, Gaulin Jeffrey, Bouchard Patricia, Villarreal Alex R, Penningroth Mitchell R, Crone Kathryn K, Vogt Grace A, Gilbertsen Adam J, Ayotte Yann, Coutinho de Oliveira Luciana, Serrano-Wu Michael H, Drouin Nathalie, Hung Deborah T, Hunter Ryan C, Carlson Erin E

Targeting a highly conserved domain in bacterial histidine kinases to generate inhibitors with broad spectrum activity

靶向细菌组氨酸激酶中高度保守的结构域,以生成具有广谱活性的抑制剂

Fihn, Conrad A; Carlson, Erin E

Investigation of an ALDH1A1-specific inhibitor for suppression of weight gain in a diet-induced mouse model of obesity

研究ALDH1A1特异性抑制剂对饮食诱导肥胖小鼠模型体重增加的抑制作用

Haenisch, Michael; Nguyen, Tai; Fihn, Conrad A; Goldstein, Alex S; Amory, John K; Treuting, Piper; Brabb, Thea; Paik, Jisun

Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition

筛选丝氨酸/苏氨酸和酪氨酸激酶抑制剂以抑制组氨酸激酶

Wilke, Kaelyn E; Fihn, Conrad A; Carlson, Erin E